Patricia H. Janak
Johns Hopkins University
159 Papers
2K Citations
Patricia H. Janak is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Nucleus accumbens & Ventral tegmental area. The author has an hindex of 60, co-authored 147 publications. Previous affiliations of Patricia H. Janak include University of North Carolina at Chapel Hill & University of Lausanne.
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Papers
Behavioral assessment of forgetting in aged rodents and its relationship to peripheral sympathetic function.
TL;DR: It is suggested that the adrenal medulla secretes catecholamines that act outside the blood-brain barrier to modulate memory processes, and this impairment may contribute to the rapid forgetting observed in senescent animals.
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Acamprosate attenuates cocaine- and cue-induced reinstatement of cocaine-seeking behavior in rats
M. Scott Bowers,Billy T. Chen,Jonathan Chou,Megan P. H. Osborne,Justin T. Gass,Ronald E. See,Antonello Bonci,Patricia H. Janak,M. Foster Olive +8 more
TL;DR: Acamprosate attenuates both drug- and cue-induced reinstatement of cocaine-seeking behavior, suggesting that this compound may serve as a potential treatment for preventing relapse in cocaine-addicted humans.
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Cocaine and amphetamine facilitate retention of jump-up responding in rats.
TL;DR: Both cocaine and amphetamine enhanced learning and memory under experimental conditions that allowed for drug-free training and testing.
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Responses to ethanol in C57BL/6 versus C57BL/6 × 129 hybrid mice
TL;DR: It is found that inbred B6J and B6NT mice showed greater ethanol preference and consumption than their respective hybrids when ethanol was continuously available, and it may not be necessary to backcross hybrids to an inbreeding B6 background to study many ethanol‐related behaviors in gene‐targeted mice.
Cocaine enhances retention of avoidance conditioning in rats
TL;DR: It is shown that post-training cocaine administration enhances retention of an active avoidance task in rats, and that this effect is probably independent of the anesthetic properties of the drug.
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