Pascal Polepole
University of Nebraska–Lincoln
10 Papers
27 Citations
Pascal Polepole is an academic researcher from University of Nebraska–Lincoln. The author has contributed to research in topics: Population & Virus. The author has an hindex of 5, co-authored 10 publications. Previous affiliations of Pascal Polepole include RMIT University & University of Zambia.
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Papers
Identification of human papillomaviruses from formalin-fixed, paraffin-embedded pre-cancer and invasive cervical cancer specimens in Zambia: a cross-sectional study
Allen C. Bateman,Allen C. Bateman,Katundu Katundu,Pascal Polepole,Aaron Shibemba,Mulindi H. Mwanahamuntu,Mulindi H. Mwanahamuntu,Dirk P. Dittmer,Groesbeck P. Parham,Groesbeck P. Parham,Groesbeck P. Parham,Carla J. Chibwesha,Carla J. Chibwesha +12 more
TL;DR: A combined HPV-16 and/or HPV-18 prevalence of 69.9% in ICC specimens suggests that current vaccines will be highly protective against cervical cancer in Zambia.
Amyloid precursor protein is a restriction factor that protects against Zika virus infection in mammalian brains.
Amy Lingel,Haishuang Lin,Yuval Gavriel,Eric A. Weaver,Pascal Polepole,Virginia Lopez,Yuguo Lei,Thomas M. Petro,Beka Solomon,Chi Zhang,Luwen Zhang +10 more
TL;DR: Findings suggest that APP is a restriction factor that protects against ZIKV by serving as a decoy receptor, and plays a protective role in ZikV-mediated brain injuries.
12
Application of highly portable MinION nanopore sequencing technology for the monitoring of nosocomial tuberculosis infection.
TL;DR: Preliminary data from the pediatric pneumonia study will demonstrate the detection of TB in induced sputum from children admitted to the University Teaching Hospital, Lusaka, Zambia, with many patients dying or being discharged without treatment.
12
Epstein-Barr virus-immortalized B lymphocytes exacerbate experimental autoimmune encephalomyelitis in xenograft mice.
Pascal Polepole,Alison Bartenslager,Yutong Liu,Thomas M. Petro,Thomas M. Petro,Samodha C. Fernando,Luwen Zhang +6 more
TL;DR: It is suggested that EBV‐mediated proliferation of B lymphocytes may be a risk factor for the exacerbation of MS, which is associated with gut microbiome changes and BBB modulations.
Detection of Human Herpes Virus 8 in Kaposi's sarcoma tissues at the University Teaching Hospital, Lusaka, Zambia.
Rabecca Tembo,Trevor Kaile,Doris Kafita,Chrispin Chisanga,Annie Kalonda,Ephraim Zulu,Mulemba Tillika Samutela,Pascal Polepole,Geoffrey Kwenda +8 more
TL;DR: Evidence of Human Herpes virus 8 infection in Kaposi's sarcoma tissues at the University Teaching Hospital in Lusaka, Zambia is provided and the identification of the virus in the tissues will aid in targeted therapy.