Pascal Goube
6 Papers
Pascal Goube is an academic researcher. The author has contributed to research in topics: Medicine & Percutaneous coronary intervention. The author has an hindex of 4, co-authored 6 publications.
Chat about Author
Papers
Hospital admissions for acute myocardial infarction before and after lockdown according to regional prevalence of COVID-19 and patient profile in France: a registry study
Jules Mesnier,Yves Cottin,Pierre Coste,E. Ferrari,Francois Schiele,Gilles Lemesle,Christophe Thuaire,Denis Angoulvant,Guillaume Cayla,Claire Bouleti,Romain Gallet de Saint Aurin,Pascal Goube,Thibault Lhermusier,Jean-Guillaume Dillinger,Franck Paganelli,Anis Saib,Fabrice Prunier,Gérald Vanzetto,Olivier Dubreuil,Etienne Puymirat,Franck Boccara,Hélène Eltchaninoff,Marine Cachanado,Alexandra Rousseau,Elodie Drouet,Philippe Gabriel Steg,Tabassome Simon,Nicolas Danchin +27 more
TL;DR: A marked decrease in hospital admissions was observed following the lockdown, irrespective of patient characteristics and regional prevalence of COVID-19, and health authorities should be aware of these findings, in order to adapt their message if the CO VID-19 pandemic persists or recurs, or in case of future major epidemics.
194
Ticagrelor versus clopidogrel in elective percutaneous coronary intervention (ALPHEUS): a randomised, open-label, phase 3b trial
Johanne Silvain,Benoit Lattuca,Farzin Beygui,Grégoire Rangé,Zuzana Motovska,Jean-Guillaume Dillinger,Ziad Boueri,Philippe Brunel,Thibault Lhermusier,Christophe Pouillot,Elisa Larrieu-Ardilouze,Franck Boccara,Jean-Noël Labèque,Paul Guedeney,Mohamad El Kasty,Mikael Laredo,Raphaëlle Dumaine,Gregory Ducrocq,Jean-Philippe Collet,Guillaume Cayla,Katrien Blanchart,Petr Kala,Eric Vicaut,Gilles Montalescot,Mathieu Kerneis,Nassim Braik,Olivier Barthelemy,Gérard Helft,Claude Lefeuvre,Rémi Choussat,Marie Hauguel,Michel Zeitouni,Thomas Cuisset,Jean-Louis Bonnet,Pierre Deharo,Luc Cornillet,Bertrand Ledermann,Clément Lonjon,Laurent Schmutz,Franck Albert,Thibault Demicheli,Laurent Roussel,Reda Bensaid,Christophe Thuaire,Patrick Henry,Stéphane Manzo-Silberman,Georgios Sideris,Damien Logeart,Vincent Spagnoli,Léa Cacoub,Jean Richard Vi-Fane,Jens Glasenapp,Karim Bougrini,Nicolas Combaret,Pascal Motreff,Géraud Souteyrand,Aimé Amonchot,Thomas Mouyen,Didier Carrié,Frédéric Bouisset,Thomas Chollet,Francisco Campelo-Parada,Nicolas Delarche,Francois Schiele,Mathieu Besutti,Marie Hauguel-Moreau,Rami El Mahmoud,Christophe Caussin,Mami Zoheir,Aurélie Veugeois,Alain Dibie,Olivier Varenne,Fabien Picard,Alexandre Lafont,Julien Adjedj,P. Degrell,Rémi Sabatier,Vincent Roule,Mathieux Bignon,Pierre Ardouin,Adrien Lemaitre,Clément Briet,Pascal Goube,Pierre Coste,Laura Cetran,Jérôme Clerc,Hervé Le Breton,Dominique Boulmier,Vincent Auffret,Jean-Luc Bonas,Jean-Louis Georges,Bernard Livarek,Elodie Blicq,Nicolas Baron,Géraldine Gibault-Genty,Yves Cottin,Isabelle Lhuillier,Carole Richard,Luc Lorgis,Philippe Buffet,Christian Spaulding,Nicole Karam,Etienne Puymirat,Marco G. Mennuni,Emmanuel Poulidakis,Lionel Bonnevie,Marion Chauvet,Laurie Dufour,Yann Ancedy,Stéphane Ederhy,Arnaud Etienney,Anne Bellemain-Appaix,Nathaniel Bitton,Laurent Jacq,Christophe Saint-Etienne,Florence Leclercq,François Roubille,Gilles Rioufol,François Derimay,Marc Goralski,Wael Yafi,Emmanuelle Filippi,Alain Kermarrec,Christophe Le Ray,Antoine Merlet,Aurelie Loirat,Damien Brunet,Jack Ravisy,Laurent Mock,Guillaume Molins,Max Carre,Erwan Bressollette,Luc Christiaens,Romain Cador Cador,Eric Van Belle,Gilles Lemesle,Cédric Delhaye,Flavien Vincent,Sina Porouchani,Hugues Spillemaeker,Katy Petit,Olivier Ressencourt,Vincent Humeau,François Jourda,Marc-Antoine Arnould,Stephen Chassaing,Karl Isaaz,Laurent Payot,Jacques Montsegu,Benjamin Faurie,Michel Pansieri,Marc Metge,Karim Moussa,Mathieu Pankert,Olivier Morel,Sébastien Hess,Luc Maillard,Thibault Manigold,Vincent Letocart,Julien Plessis,Pauline Berthome,Mickael Bonin,François Huchet,Emmanuel Teiger,Romain Gallet,Gauthier Mouillet,Madjid Boukantar,Mohammed Nejjari,David Attias,Mathieu Steinecker,Martin Kozel,Zdenko Stelmach,Ota Hlinomaz,Michal Rezek,Martin Novak,Jan Sitar,Jiri Semenka,Otakar Bocek,Roman Štipal,Martin Poloczek,Jan Kanovský,Petr Jerabek,Jiří Karasek,Sylvie Hruskova,Marian Branny,Jan Mrozek,Tomas Grezl,Leos Pleva,Pavel Kukla,Martin Porzer +189 more
TL;DR: Ticagrelor was not superior to clopidogrel in reducing periprocedural myocardial necrosis after elective PCI and did not cause an increase in major bleeding, but did increase the rate of minor bleeding at 30 days, which supports the use of clopinogrel as the standard of care for elective PCI.
111
Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling.
Icía Santos-Zas,Jeremie Lemarié,Ivana Zlatanova,Marine Cachanado,Jean-Christophe Seghezzi,Benamer H,Pascal Goube,Marie Vandestienne,Raphael Cohen,Maya Ezzo,Vincent Duval,Yujiao Zhang,Jin-Bo Su,Alain Bizé,Lucien Sambin,Philippe Bonnin,Maxime Branchereau,Christophe Heymes,Corinne Tanchot,José Vilar,Clément Delacroix,Jean-Sébastien Hulot,Clément Cochain,Patrick Bruneval,Nicolas Danchin,Alain Tedgui,Ziad Mallat,Ziad Mallat,Tabassome Simon,Bijan Ghaleh,Jean-Sébastien Silvestre,Hafid Ait-Oufella +31 more
TL;DR: In this paper, the authors show that following acute myocardial infarction in mice, CD8+ T lymphocytes are recruited and activated in the ischemic heart tissue and release Granzyme B, leading to cardiomyocyte apoptosis, adverse ventricular remodeling and deterioration of myocardia.
A sirolimus-eluting bioabsorbable polymer-coated stent (MiStent) versus an everolimus-eluting durable polymer stent (Xience) after percutaneous coronary intervention (DESSOLVE III): a randomised, single-blind, multicentre, non-inferiority, phase 3 trial
Robbert J. de Winter,Yuki Katagiri,Taku Asano,Krzysztof Milewski,Philipp Lurz,Paweł Buszman,Gillian A.J. Jessurun,Karel T. Koch,Roland P.T. Troquay,Bas J B Hamer,Ton Oude Ophuis,Jochen Wöhrle,Rafał Wyderka,Guillaume Cayla,Sjoerd H. Hofma,Sébastien Levesque,Aleksander Żurakowski,Dieter Fischer,Maciej Kośmider,Pascal Goube,E. Karin Arkenbout,Michel Noutsias,Markus Ferrari,Yoshinobu Onuma,William Wijns,Patrick W. Serruys +25 more
TL;DR: The sirolimus-Eluting bioabsorbable polymer stent was non-inferior to the everolimus-eluting durable polymer stents for a device-oriented composite clinical endpoint at 12 months in an all-comer population.
94
Hospital Admissions for Acute Myocardial Infarction Before and After Lockdown According to Regional Prevalence of COVID-19 and Patient Profile
Jules Mesnier,Yves Cottin,Pierre Coste,E. Ferrari,Francois Schiele,Gilles Lemesle,Christophe Thuaire,Denis Angoulvant,Guillaume Cayla,Claire Bouleti,Romain Gallet de Saint Aurin,Pascal Goube,Thibault Lhermusier,Jean-Guillaume Dillinger,Franck Paganelli,Anis Saib,Fabrice Prunier,Gérald Vanzetto,Olivier Dubreuil,Etienne Puymirat,Franck Boccara,Hélène Eltchaninoff,Marine Cachanado,Alexandra Rousseau,Elodie Drouet,Gabriel Steg,Tabassome Simon,Nicolas Danchin +27 more
TL;DR: A marked decrease in hospital admissions was observed following the lockdown, irrespective of patient characteristics and regional prevalence of COVID-19, in order to adapt their message in case of a second wave of the pandemic or future major epidemics.