Paolo Boscolo-Rizzo

TL;DR: In this article , a commentary on the article by Hosseinpoor et al. is presented, which is based on the Laryngoscope article by Hajiaghayi et al., 2012.

TL;DR: Beware of the dangers along the path towards the diagnosis of HPV-driven oropharyngeal squamous cell carcinoma, as several ongoing clinical trials are exploring the feasability of treatment de-escalation in this subset of OPSCC in the attempt to reduce toxicity, while maintaining the same efficacy of traditional treatment regimens.

TL;DR: In this paper , the authors investigated the association between five different inflammatory blood markers and several oncological outcomes, including local, regional, and distant failure, disease-free survival (DFS), and overall survival (OS).

Abstract: The objective of this study was to compare the efficacy of supportive periodontal therapy (i.e. scaling and rooth planning, SRP) alone versus a chemical device silica dioxide (SiO2) colloidal solutions (SDCS) used in association with SRP in the treatment of chronic periodontitis in adult patients. A total of 20 patients with a diagnosis of chronic periodontitis (40 localized chronic periodontitis sites) in the age group of 35 to 55 were selected. None of these patients have previously received any surgical or non-surgical periodontal therapy and demonstrated radiographic evidence of moderate bone loss. Two non-adjacent sites in separate quadrants were selected in each patient to monitorize treatment efficacy (split mouth design). Clinical pocket depth (PD) and microbial analysis (MA) were analyzed at baseline and 15th day. SPSS program and paired simple statistic T-test were used to detect significant differences. Total bacteria loading, Tannerella Forsitia and Treponema Denticola loading were statistically reduced when SiO2 is locally delivered. SDCS gel is an adjuvant therapy which should be added to SRP in the management of moderate to severe chronic periodontitis.