Pablo Caruana
6 Papers
Pablo Caruana is an academic researcher. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 3, co-authored 4 publications.
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Papers
Nano-Based Approved Pharmaceuticals for Cancer Treatment: Present and Future Challenges
Francisco Rodríguez,Pablo Caruana,Noa de la Fuente,Pia Español,M. Idoia Gámez,Josep Balart,Elisa Llurba,Ramon Rovira,Raúl Ruiz,Cristina Martin-Lorente,José Luis Corchero,María Virtudes Céspedes +11 more
TL;DR: An overview of the approved nanomedicine for cancer treatment and the rationale behind their designs and applications is provided and the new approaches that are currently under investigation are highlighted, focusing on the tumor microenvironment and tumor disseminate cells as the most attractive and effective strategies for cancer treatments.
Neural plasticity of the uterus: New targets for endometrial cancer?
Pia Español,Rocio Luna,Cristina Soler,Pablo Caruana,Amanda Altés-Arranz,Francisco Rodríguez,O. Porta,O. Sánchez,Elisa Llurba,Ramon Rovira,María Virtudes Céspedes +10 more
TL;DR: This review compiles information on the architecture and function of autonomous uterine neural innervations and the influence of hormone-dependent nerves in normal uterus and tumor progression and explores new therapeutic possibilities for endometrial cancer using these endocrine and neural advantages.
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Lenvatinib-Loaded Poly(lactic-co-glycolic acid) Nanoparticles with Epidermal Growth Factor Receptor Antibody Conjugation as a Preclinical Approach to Therapeutically Improve Thyroid Cancer with Aggressive Behavior
Giovanna Revilla,Nuseibah Al Qtaish,Pablo Caruana,Myriam Sainz-Ramos,Tania Belen Lopez-Mendez,Francisco Rodríguez,Verónica Paez-Espinosa,Changda Li,Núria Vallverdú,Maria Edwards,Antonio Moral,Jose Ignacio Arias Perez,J. C. Escolà-Gil,José Luis Pedraz,Idoia Gallego,Rosa Corcoy,María Virtudes Céspedes,Gustavo Puras,Eugènia Mato +18 more
TL;DR: These proof-of-concept findings suggest a promising strategy for administering TKIs in a more targeted and effective manner, as decorated NPs exhibited enhanced parameters related to apoptotic/karyolytic forms, mitotic index, and vascularization compared with NPs without decoration.
2
Shaping the future one slice at a time: How 3D organotypic tumour slice models are driving drug discovery in ovarian cancer.
Maria Edwards,Pablo Caruana,Mireia Escar,María Virtudes Céspedes +3 more
Abstract: Highlights • OTSC represents tumour complexity and more realistic drug response data in screening novel agents and drug combinations.• OTSC provides rapid insights into patient-specific drug responses and biomarker validation for drug resistance.• OTSC could aid in exploring novel multitarget therapies and innovative drug delivery systems against TME vulnerabilities.