21 Papers
122 Citations
P. Varma is an academic researcher from University of Texas at San Antonio. The author has contributed to research in topics: Dispersion relation & Alfvén wave. The author has an hindex of 7, co-authored 21 publications. Previous affiliations of P. Varma include Council of Scientific and Industrial Research.
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Papers
A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy.
Zane R. Lybrand,Zane R. Lybrand,Sonal Goswami,Jingfei Zhu,Veronica Jarzabek,Nikolas Merlock,Mahafuza Aktar,Courtney Smith,Ling Zhang,P. Varma,Kyung-Ok Cho,Shaoyu Ge,Jenny Hsieh +12 more
TL;DR: In this article, the authors identify a critical window of activity associated with the aberrant maturation of adult-born granule cells (abGCs) characterized by abnormal dendrite morphology, ectopic migration, and spontaneous recurrent seizures (SRS).
Nuclear matrix proteome analysis of Drosophila melanogaster
TL;DR: A subset of NuMat proteins remains associated with the mitotic chromosomes, implicating their role in mitosis and possibly the epigenetic cellular memory, and NuMat proteome analysis provides tools and opens up ways to understand nuclear organization and function.
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Targeting Seizure-Induced Neurogenesis in a Clinically Relevant Time Period Leads to Transient But Not Persistent Seizure Reduction.
TL;DR: Evidence is provided that seizure-induced neurogenesis when adequately reduced in a clinically relevant time period has the potential to transiently suppress recurrent seizures, but additional mechanisms need to be targeted to permanently prevent epilepsy development.
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Dynamics of nuclear matrix proteome during embryonic development in Drosophila melanogaster
P. Varma,Rakesh Mishra +1 more
TL;DR: This study establishes links between the dynamics of nuclear architecture and embryonic development and provides tools to further understand the process such as cellular differentiation in the context of higher-order nuclear organization.
Novel Targets of SARS-CoV-2 Spike Protein in Human Fetal Brain Development Suggest Early Pregnancy Vulnerability
TL;DR: In this article, the authors analyzed the expression of known (ACE2, TMPRSS2, and FURIN) and novel (ZDHHC5, GOLGA7, and ATP1A1) S protein interactors in publicly available fetal brain bulk and single cell RNA sequencing datasets.