P.-V. Malathy
University of Missouri
7 Papers
70 Citations
P.-V. Malathy is an academic researcher from University of Missouri. The author has contributed to research in topics: Trophoblast & Complementary DNA. The author has an hindex of 7, co-authored 7 publications.
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Papers
Molecular Cloning and Characterization of Complementary Deoxyribonucleic Acids Corresponding to Bovine Trophoblast Protein-1: A Comparison with Ovine Trophoblast Protein-1 and Bovine Interferon-αII
K. Imakawa,Thomas R. Hansen,P.-V. Malathy,R. V. Anthony,H. G. Polites,K. R. Marotti,R. M. Roberts +6 more
TL;DR: In this paper, a series of recombinant cDNA clones corresponding to the mRNA for bTP-1 have been isolated from cDNA libraries representing day 18−19 bovine conceptus poly(A)+ mRNA.
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Interferon production by the preimplantation sheep embryo.
R. M. Roberts,K. Imakawa,Y. Niwano,Mohammad Kazemi,P.-V. Malathy,T R Hansen,A.A. Glass,L.H. Kronenberg +7 more
TL;DR: It is confirmed that oTP-1, which at days 15-17 of pregnancy is produced by a single embryo at more than 100 micrograms (greater than 1 million antiviral units) per day, is a functional IFN.
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Complex Binding of the Embryonic Interferon, Ovine Trophoblast Protein-1, to Endometrial Receptors
TL;DR: Evidence is provided that the binding parameters of oTP-1 and rBoIFN-alpha I1 to endometrial receptors are different, and this work states that ovine trophoblast protein-1 is a 172-amino-acid polypeptide which has been suggested to be the causal agent in maternal recognition of pregnancy in the ewe.
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Molecular cloning of the uteroferrin- associated protein, a major progesterone-induced serpin secreted by the porcine uterus, and the expression of its mRNA during pregnancy.
TL;DR: Comparison of the NH2-terminal sequences of the individual UfAP poly-peptides with the amino acid sequence deduced from the cDNA has indicated a series of at least four posttranslational proteolytic processing steps which generate the various molecular forms of the Uf AP.
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Ovine trophoblast protein-1 and bovine trophoblast protein-1 are present as specific components of uterine flushings of pregnant ewes and cows.
TL;DR: Results of this study show that oTP-1 and bTB-1 are pregnancy-specific proteins that are secreted into the uterine lumen where they possibly exert a local response.
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