P. McLaughlin
University of Texas at Austin
39 Papers
784 Citations
P. McLaughlin is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Lymphoma & Follicular lymphoma. The author has an hindex of 20, co-authored 39 publications.
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Papers
Stage I-II follicular lymphoma. Treatment results for 76 patients.
P. McLaughlin,Lillian M. Fuller,William S. Velasquez,Jane A. Sullivan-Halley,James J. Butler,Fernando Cabanillas +5 more
TL;DR: The RFS was significantly better for patients receiving chemotherapy with or without XRT than for XRT alone (64% versus 37% at 5 years, P = 0.02), despite a higher frequency of adverse prognostic features in the chemotherapy‐treated group.
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The gene located at chromosome 18 band q21 is rearranged in uncultured diffuse lymphomas as well as follicular lymphomas
M. S. Lee,Mark Blick,Sen Pathak,Jennifer M. Trujillo,James J. Butler,Ruth L. Katz,P. McLaughlin,Fredrick B. Hagemeister,William S. Velasquez,Angela Goodacre +9 more
TL;DR: Using two human genomic DNA fragments cloned from the chromosome 18 band q21 as probes, the Southern blot technique proved helpful in difficult karyotyping situations and detected rearrangement of the 18q21 gene in 10 of 13 cases in which the t(14;18)(q32;q21) translocation was found by cytogenetic techniques.
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Cytogenetic features of Hodgkin's disease suggest possible origin from a lymphocyte.
Fernando Cabanillas,Sen Pathak,Jennifer M. Trujillo,Grace Grant,Ann Cork,Fredrick B. Hagemeister,William S. Velasquez,P. McLaughlin,J. R. Redman,Ruth L. Katz +9 more
TL;DR: Tumor samples from 49 patients were studied to determine if any chromosomal abnormalities that could add further information to this controversial point are present, and the most common breakpoints were in 11q23, 14q32, 6q11-21, and 8q22-24.
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Hodgkin's disease: Study of treatment intensities and incidences of second malignancies
Maria A Rodriguez,Lillian M. Fuller,S. O. Zimmerman,Pamela K. Allen,Barry W. Brown,M. F. Munsell,Fredrick B. Hagemeister,P. McLaughlin,William S. Velasquez,F. Swan,F. F. Cabanillas +10 more
TL;DR: The analysis suggests that the most critical host factor for developing a second malignancy was age, and the combination of age and stage was the most significant risk factor for AML and non-Hodgkin's lymphoma.
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The association of specific "favorable" cytogenetic abnormalities with secondary leukemia.
Hagop M. Kantarjian,Hagop M. Kantarjian,Michael J. Keating,Ronald S. Walters,Miloslav Beran,P. McLaughlin,Kenneth B. McCredie,And Emil J. Freireich +7 more
TL;DR: Eight patients with secondary leukemia and specific cytogenetic abnormalities involving inversion of chromosome 16, or translations between chromosomes 15 and 17, or 8 and 21, are presented and seven of them achieved complete remission with chemotherapy.
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