P Langmann
University of Würzburg
22 Papers
364 Citations
P Langmann is an academic researcher from University of Würzburg. The author has contributed to research in topics: Ritonavir & Saquinavir. The author has an hindex of 14, co-authored 22 publications.
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Papers
•Journal Article
No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment.
Ralf Winzer,P Langmann,Michael Zilly,Franz Tollmann,Jörg Schubert,Hartwig Klinker,Benedikt Weissbrich +6 more
TL;DR: A retrospective study of HIV patients under antiretroviral therapy did not find evidence for an influence of the MDR1 3435 genotype on plasma levels of LPV and EFV.
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Lipid lowering therapy with fluvastatin and pravastatin in patients with HIV infection and antiretroviral therapy: comparison of efficacy and interaction with indinavir.
Andreas Benesic,Michael Zilly,Kluge F,Benedikt Weissbrich,Ralf Winzer,Hartwig Klinker,P Langmann +6 more
TL;DR: Fluvastatin and pravastatin are efficient in lowering total and LDL cholesterol levels in HIV-positive patients receiving HAART, and both compounds seem to be a viable treatment option in HAART-induced hypercholesterolemia.
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•Journal Article
Efavirenz plasma levels for the prediction of treatment failure in heavily pretreated HIV-1 infected patients.
TL;DR: An individual EFV plasma level below 1.000 ng/ml in one single measurement seems to be predictive of viral failure and the developement of genotypic resistance.
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Simultaneous determination of voriconazole and posaconazole concentrations in human plasma by high-performance liquid chromatography.
Kathrin Kahle,P Langmann,Diana Schirmer,Ulrike Lenker,Daniela Keller,Annegret Helle,Hartwig Klinker,Werner J. Heinz +7 more
TL;DR: A simple, sensitive, and selective high-performance liquid chromatographic method for the simultaneous determination of voriconazole and posaconazole concentrations in human plasma was developed and validated and quantitative recovery following liquid-liquid extraction with diethyl ether was achieved.
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High-performance liquid chromatographic method for the determination of HIV-1 non-nucleoside reverse transcriptase inhibitor efavirenz in plasma of patients during highly active antiretroviral therapy.
TL;DR: A new high-performance liquid chromatographic method for the determination of efavirenz in human plasma is described, and quantitative recovery following liquid-liquid extraction with diethylether from 200 microl of human plasma was achieved.
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