P. Lan
6 Papers
P. Lan is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 6 publications.
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Papers
Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression
Qian Zhang,Xiaoya Yang,Jinjie Wu,Shu-Biao Ye,Junli Gong,Wai Ming Cheng,Zhanhao Luo,Jing Yu,Yugeng Liu,Wanyi Zeng,Chen Liu,Zhi G. Xiong,Yuan Chen,Zhen He,P. Lan +14 more
TL;DR: Zhang et al. as discussed by the authors identified that metabolic enzyme acyl-CoA oxidase 1 (ACOX1) suppresses colorectal cancer (CRC) progression by regulating palmitic acid (PA) reprogramming.
Unintrusive multi-cancer detection by circulating cell-free DNA methylation sequencing (THUNDER): development and independent validation studies.
Qiang Gao,Y.P. Lin,B-sh Li,G.Q. Wang,Lin Dong,B. Shen,Wenhui Lou,Wen-Chih Wu,Danhong Ge,Q. Zhu,Y Xu,J. Xu,W. Chang,P. Lan,M. J. He,Guangyu Qiao,Shaochuan Chuai,Rongyu Zang,T. Shi,Lixing Tan,Junhao Yin,Q Zeng,Xiaofang Su,Z-D Wang,X.Q. Zhao,Weihong Nian,S. Zhang,J. Zhou,Sun-Li Cai,Z. Zhang,Joan Fan +30 more
TL;DR: In this paper , the authors evaluated the performance of enhanced linear-splinter amplification sequencing, a previously described cell-free DNA (cfDNA) methylation-based technology, in the early detection and localization of six types of cancers in the colorectum, esophagus, liver, lung, ovary, and pancreas.
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Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8+ T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer
Peisi Li,Daohong Zhou,Dong-Wen Chen,Yi Kan Cheng,Yuan Chen,Zhen Lin,Zhihong Huang,Jiawei Cai,Wen-Feng Huang,Yan-Yun Lin,Hao Ke,Jia Long,Yifeng Zou,Shu Biao Ye,P. Lan +14 more
TL;DR: In this paper , the expression of IFI35 was found to be correlated with increased proliferation and cytotoxicity of CD8 + T cells in colorectal cancer cells and increased the efficacy of CAR-T cells in immunotherapeutic treatment.
High-throughput proteomics profiling-derived signature associated with chemotherapy response and survival for stage II/III colorectal cancer
Shu Biao Ye,Yi Kan Cheng,Peisi Li,Lin Zhang,Lianhai Zhang,Yan Huang,Ping Chen,Yian Wang,Chao Wang,Jianhong Peng,Lisa Ling,Xiaojian Wu,Jun Qin,Zihuan Yang,P. Lan +14 more
TL;DR: Wang et al. as mentioned in this paper used high-throughput proteomics to analyze tumor and adjacent normal tissues of stage II/III colorectal cancer patients with /without relapse to identify potential markers for predicting prognosis and benefit from ACT.