P. Doering
Aarhus University
8 Papers
60 Citations
P. Doering is an academic researcher from Aarhus University. The author has contributed to research in topics: Zinc & Biology. The author has an hindex of 8, co-authored 8 publications.
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Papers
Kupffer cells are central in the removal of nanoparticles from the organism
Evaldas Sadauskas,Håkan Wallin,Meredin Stoltenberg,Ulla Vogel,P. Doering,Agnete Larsen,Gorm Danscher +6 more
TL;DR: In inert gold nanoparticles do not penetrate cell membranes by non-endocytotic mechanisms, but are rather taken up by endocytosis; part of these tiny nanoparticles are released into the urine as a result of simple filtration in the renal glomeruli.
Gold ions bio-released from metallic gold particles reduce inflammation and apoptosis and increase the regenerative responses in focal brain injury
Agnete Larsen,Kristian Kolind,Dan Sonne Pedersen,P. Doering,Mie Østergaard Pedersen,Gorm Danscher,Milena Penkowa,Meredin Stoltenberg +7 more
TL;DR: It is concluded that bio-liberated gold ions possess pronounced anti-inflammatory and neuron-protective capacities in the brain and it is suggested that metallic gold has clinical potentials.
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Chemical Blocking of Zinc Ions in CNS Increases Neuronal Damage Following Traumatic Brain Injury (TBI) in Mice
TL;DR: This study revealed that chemical blocking of vesicular zinc ions, either by chelation with DEDTC or accumulation in zinc-selenium nanocrystals, worsened the effects on the aftermath of TBI in the WT mice by increasing the number of necrotic and apoptotic cells within the first 24 hours after TBI, when compared to those of chemically untreated WT mice.
Zinc ions in the endocrine and exocrine pancreas of zinc deficient rats.
TL;DR: The present findings suggest that the endocrine pancreas is able to compensate for the subclinical zinc deficiency as it maintains an adequate zinc ion level in the secretory vesicles for insulin storage, as compared with the exocrine Pancreas, which exhibits decreased levels of zinc ion staining as a consequence of 4 weeks of reduced zinc intake.
Changes in the vesicular zinc pattern following traumatic brain injury.
TL;DR: It is speculated that vesicular zinc may not contribute to neuronal damage following TBI, because in vivo created ZnSe nanocrystals were confined to the cytoplasm of the somata and their proximal dendrites.
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