P. Andrew Futreal
University of Texas MD Anderson Cancer Center
350 Papers
1K Citations
P. Andrew Futreal is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 107, co-authored 245 publications. Previous affiliations of P. Andrew Futreal include Wellcome Trust & Wellcome Trust Sanger Institute.
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Papers
Author response: Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
Young Seok Ju,Ludmil B. Alexandrov,Moritz Gerstung,Inigo Martincorena,Serena Nik-Zainal,Manasa Ramakrishna,Helen Davies,Elli Papaemmanuil,Gunes Gundem,Adam Shlien,Niccolo Bolli,Sam Behjati,Patrick S. Tarpey,Jyoti Nangalia,Jyoti Nangalia,Jyoti Nangalia,Charles E. Massie,Charles E. Massie,Charles E. Massie,Adam Butler,Jon W. Teague,George S. Vassiliou,George S. Vassiliou,George S. Vassiliou,Anthony R. Green,Anthony R. Green,Ming-Qing Du,Ashwin Unnikrishnan,John E. Pimanda,Bin Tean Teh,Nikhil C. Munshi,Mel Greaves,Paresh Vyas,Adel K. El-Naggar,Tom Santarius,V. Peter Collins,Richard Grundy,Jack A. Taylor,D. Neil Hayes,David Malkin,Christopher S. Foster,Anne Y. Warren,Hayley C. Whitaker,Daniel Brewer,Daniel Brewer,Rosalind A. Eeles,Colin Cooper,Colin Cooper,David E. Neal,Tapio Visakorpi,William B. Isaacs,G. Steven Bova,Adrienne M. Flanagan,Adrienne M. Flanagan,P. Andrew Futreal,P. Andrew Futreal,Andy G. Lynch,Patrick F. Chinnery,Ultan McDermott,Ultan McDermott,Michael R. Stratton,Peter J. Campbell,Peter J. Campbell,Peter J. Campbell +63 more
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FusionPathway: Prediction of pathways and therapeutic targets associated with gene fusions in cancer.
TL;DR: This work developed a domain-based network approach to infer the pathways of fusions and demonstrated the capabilities of this approach by primarily applying it to the well-studied BCR-ABL1 fusion, and successfully identified known genes and pathways associated with these fusions.
Cancer Genomics in Clinical Context
TL;DR: An adaptive learning platform, APOLLO™ (adaptive patient-oriented longitudinal learning and optimization) designed to integrate genomic research in the context of, but not in the path of, routine and investigational clinical care for purposes of enabling data-driven discovery across disciplines such that every patient can contribute to and potentially benefit from research discoveries.
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Analysis of Immune Intratumor Heterogeneity Highlights Immunoregulatory and Coinhibitory Lymphocytes as Hallmarks of Recurrence in Stage I Non-Small Cell Lung Cancer.
Alejandro Francisco-Cruz,Pedro P. Rocha,Alexandre Reuben,Santhoshi Krishnan,Priyam Das,Runzhe Chen,Kelly Quek,Jun Li,Edwin R. Parra,Luisa M. Solis,Souptik Barua,Mei Jiang,Rossana Lazcano,Chi Wan Chow,Carmen Behrens,Curtis Gumb,Latasha Little,Junya Fukuoka,Neda Kalhor,Annikka Weissferdt,Humam Kadara,John V. Heymach,Stephen G. Swisher,Boris Sepesi,Arvind Rao,Cesar A. Moran,Jian Zhang,J. J. Lee,Junya Fujimoto,P. Andrew Futreal,Ignacio I. Wistuba,Christine B. Peterson,Jianjun Zhang +32 more
TL;DR: In this paper , the authors used multiregion multiplex immunofluorescence (MIMO) to characterize ITH at the immune cell level along with whole exome and T cell repertoire sequencing from the same tumor regions.
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Supplementary file 3.
Young Seok Ju,Ludmil B. Alexandrov,Moritz Gerstung,Inigo Martincorena,Serena Nik-Zainal,Manasa Ramakrishna,Helen Davies,Elli Papaemmanuil,Gunes Gundem,Adam Shlien,Niccolo Bolli,Sam Behjati,Patrick S. Tarpey,Jyoti Nangalia,Charles E. Massie,Adam Butler,Jon W. Teague,George S. Vassiliou,Anthony R. Green,Ming-Qing Du,Ashwin Unnikrishnan,John E. Pimanda,Bin Tean Teh,Nikhil C. Munshi,Mel Greaves,Paresh Vyas,Adel K. El Naggar,Tom Santarius,V. Peter Collins,Richard Grundy,Jack A. Taylor,D. Neil Hayes,David Malkin,Christopher S. Foster,Anne Y. Warren,Hayley C. Whitaker,Daniel Brewer,Rosalind A. Eeles,Colin Cooper,David E. Neal,Tapio Visakorpi,William B. Isaacs,G. Steven Bova,Adrienne M. Flanagan,P. Andrew Futreal,Andy G. Lynch,Patrick F. Chinnery,Ultan McDermott,Michael R. Stratton,Peter J. Campbell +49 more
- 01 Jan 2014
TL;DR: All analysed strains originate from single hybridisation event, as most of LOH events are shared by all strains, and some selected duplications and deletions among those longer than 5Kb are represented.
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