P. Andrew Futreal
University of Texas MD Anderson Cancer Center
350 Papers
1K Citations
P. Andrew Futreal is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 107, co-authored 245 publications. Previous affiliations of P. Andrew Futreal include Wellcome Trust & Wellcome Trust Sanger Institute.
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Papers
Comparative genomics of high grade neuroendocrine carcinoma of the cervix.
R. Tyler Hillman,Robert J. Cardnell,Junya Fujimoto,Won-Chul Lee,Jianjun Zhang,Lauren Averett Byers,Preetha Ramalingam,Mario M. Leitao,Elizabeth M. Swisher,P. Andrew Futreal,Michael Frumovitz +10 more
TL;DR: Comparative genomics data suggest that NECC may be genetically more similar to common cervical cancer subtypes than to extra-cervical small cell neuroendocrine carcinomas of the lung and bladder, which may have implications for the selection of cytotoxic and targeted therapy regimens for this rare disease
Features of non-activation dendritic state and immune deficiency in blastic plasmacytoid dendritic cell neoplasm (BPDCN)
Hannah C. Beird,Maliha Khan,Feng Wang,Mansour Alfayez,Tianyu Cai,Li Zhao,Joseph D. Khoury,P. Andrew Futreal,Marina Konopleva,Naveen Pemmaraju +9 more
TL;DR: The serum cytokine profile analysis showed significantly elevated levels of eosinophil chemoattractants eotaxin and RANTES in BPDCN as compared with AML, suggesting a possible pre-inflammatory context of this disease, in which BPD CN features nonactivated pDCs.
Novel consensus DNA-binding sequence for BRCA1 protein complexes.
P. Lou Ann Cable,P. Lou Ann Cable,Cindy A. Wilson,Frank J. Calzone,Frank J. Rauscher,Ralph Scully,David M. Livingston,Leping Li,Courtney B. Blackwell,P. Andrew Futreal,Cynthia A. Afshari +10 more
TL;DR: A role for endogenous BRCA1 protein complexes in transcription via a defined DNA‐binding sequence is established and indicates that one function of BRC a1 is to co‐regulate the expression of genes involved in various cellular processes.
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Clonal Dynamics and Clinical Implications of Post-Remission Clonal Hematopoiesis in Acute Myeloid Leukemia (AML)
Tomoyuki Tanaka,Kiyomi Morita,Sanam Loghavi,Feng Wang,Ken Furudate,Yuya Sasaki,Latasha Little,Curtis Gumbs,Jairo Matthews,Naval Daver,Naveen Pemmaraju,Courtney D. DiNardo,Koji Sasaki,Musa Yilmaz,Tapan M. Kadia,Farhad Ravandi,Marina Konopleva,Hagop M. Kantarjian,Richard E. Champlin,Gheath Alatrash,Guillermo Garcia-Manero,Sa A. Wang,P. Andrew Futreal,Koichi Takahashi +23 more
TL;DR: DISCLOSURES DiNardo: celgene: Consultancy, Honoraria; abbvie: Consultancies, Honouraria; syros:Honoraria; notable labs: Membership on an entity's Board of Directors or advisory committees; daiichi sankyo: Honoraria
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Spatio-Temporal Genomic Heterogeneity, Phylogeny, and Metastatic Evolution in Salivary Adenoid Cystic Carcinoma.
Bin Liu,Yoshitsugu Mitani,Xiayu Rao,Mark Zafereo,Jianjun Zhang,Jianhua Zhang,P. Andrew Futreal,Guillermina Lozano,Adel K. El-Naggar +8 more
TL;DR: This study delineated clonal and subclonal phylogeny for primary and metastatic ACC, defined early genetic drivers, and provides a conceptual framework for a rational strategy to integrate heterogeneity in clinical assessment.