Ozge Danisment
Queen's University
4 Papers
Ozge Danisment is an academic researcher from Queen's University. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 2, co-authored 2 publications.
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Papers
Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation.
Yasuaki Shida,Natalia Rydz,David Stegner,Christine Brown,Jeffrey Mewburn,Kate Sponagle,Ozge Danisment,Bredon Crawford,Barbara Vidal,Carol Hegadorn,Cynthia M. Pruss,Bernhard Nieswandt,David Lillicrap +12 more
TL;DR: In this article, the von Willebrand factor (VWF) A3 domain was found to be abnormally missense in patients with a mild bleeding phenotype, and the analysis of these aberrant VWF-collagen interactions has been limited.
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Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
Justin Chee,Louise Lanoue,Dave Clary,Kendall Higgins,Lynette Bower,Ann M. Flenniken,Ruolin Guo,David J. Adams,Fatima Bosch,Robert Braun,Steve D.M. Brown,H. J. Chin,Mary E. Dickinson,Chih-Wei Hsu,Michael Dobbie,Xiang Gao,Sanjeev Galande,Anne Grobler,Jason D. Heaney,Yann Herault,Martin Hrabé de Angelis,Fabio Mammano,Lauryl M. J. Nutter,Helen Parkinson,Chuan Qin,Toshihiko Shiroishi,Radislav Sedlacek,Je Kyung Seong,Ying Xu,Cheryl L. Ackert-Bicknell,Douglas J. Adams,Anne T. Adoum,Juan Antonio Aguilar-Pimentel,Uchechukwu Akoma,Dalila Ali-Hadji,Oana V. Amarie,Philippe André,Aurelie Auburtin,Chaouki Bam’Hamed,Johannes Beckers,Joachim Beig,Zorana Berberovic,Alexandr Bezginov,Marie-Christine Birling,Katharina Boroviak,Joanna Bottomley,Antje Bürger,Dirk H. Busch,Natalie C. Butterfield,Pilar Cacheiro,Julia Calzada-Wack,Emma L. Cambridge,Susan Camilleri,Marie-France Champy,Heather Cater,Philippe Charles,Elissa J. Chesler,Yi-Li Cho,Audrey E. Christiansen,Valentina Cipriani,Nicola Cockle,Gemma F. Codner,Amie Creighton,Maribelle Cruz,Katharine F. Curry,Abigail J. D’Souza,Ozge Danisment,Daniel J. Delbarre,Hannah F. Dewhurst,Brendan Doe,Alex Dorr,Florian Giesert,Graham Duddy,Kyle Duffin,Amal El Amri,Hillary Elrick,Mohammad Eskandarian,Martin Fray,Anthony David Frost,Helmut Fuchs,Valerie Gailus-Durner,K. K. Gampe,M Ganguly,David Gannon,Lillian Garrett,Marina Gertsenstein,Diane Gleeson,Leslie P. Goodwin,Jochen Graw,Kristin N Grimsrud,Hamed Haselimashhadi,Liane Hobson,Andreas Hörlein,Sabine M. Hölter,Seung-Hyun Hong,Neil R. Horner,Amanda G. Trainor,Ziyue Huang,Coleen Kane,Yulia Katsman,Lance C. Keith,Lois Kelsey,Janet Kenyon,Ruairidh King,Piia Keskivali-Bond,Andrea Kirton,Tanja Klein-Rodewald,Thomas Klopstock,Davide Komla-Ebri,Tomasz Konopka,R Kühn,Fiona Kussy,David T Lafont,Qing Lan,Denise G. Lanza,Valerie Laurin,Elise le Marchand,Sophie Leblanc,Victoria D. Leitch,Christopher J. Lelliott,Christoph Lengger,Lauri G. Lintott,John G. Logan,Isabel Lorenzo,Ann-Marie Mallon,Naila S. Mannan,Susan Marschall,Melissa L. McElwee,Matthew Mckay,Robbie S. B. McLaren-Jones,Jeremy Mason,Terrence F. Meehan,David Miller,Michayla A Moore,Violeta Muñoz-Fuentes,Stephen A. Murray,Dong Thi Nguyen-Bresinsky,Oskar Oritz,Panos Pandis,A. Parlog,Amit N. Patel,Guillaume Pavlovic,Monica Pereira,Kevin A. Peterson,Vivek M. Philip,Andrea S. Pollard,Jan Prochazka,Dawei Qu,Ayexa Ramirez,Sean Rangarajan,Tara L. Rasmussen,Birgit Rathkolb,Mike Relac,Kyle Roberton,W. Roper,Stéphane Rousseau,David W. Rowe,Jan Rozman,Jennifer L Ryan,Edward Ryder,Luis Santos,Adrian Sanz-Moreno,Joel Schick,Zachary Seavey,John R. Seavitt,Claudia Seisenberger,Mohammed Selloum,Xueyuan Shang,Dong-Guk Shin,Michelle Simon,Gillian T. Sleep,Damian Smedley,Tania Sorg,Penny C. Sparkes,Nadine Spielmann,Ralph Steinkamp,Michelle Stewart,Claudia Stoeger,Ewan Straiton,Karen L. Svenson,H. K. Swash,Lydia Teboul,Sandra Tondat,Irina Treise,Catherine Tudor,Rachel Urban,Valerie E. Vancollie,Laurent Vasseur,Igor Vukobradovic,Hannah Wardle-Jones,Jonathan Warren,Marie Wattenhofer-Donzé,Sara Wells,Jacqueline K. White,Jean-Paul Wiegand,Amelia M Willett,Catherine Witmeyer,Eckhard Wolf,Leeyean Wong,Joshua A Wood,Wolfgang Wurst,Catherine Xu,Annemarie Zimprich,Brian P. Brooks,Colin McKerlie,Kck Lloyd,Henrik Westerberg,Ala Moshiri +207 more
TL;DR: The authors identified novel genes and pathways required for early eye development through systematic forward screening of the mammalian genome, and used the International Mouse Phenotyping Consortium (IMPC) database (data release 17.0, August 01, 2022) to identify 74 unique knockout lines (genes) with genetically associated eye defects in mouse embryos.
Mendelian gene identification through mouse embryo viability screening
Pilar Cacheiro,Henrik Westerberg,Jesse Mager,Mary E. Dickinson,Lauryl M. J. Nutter,Violeta Muñoz-Fuentes,Chih-Wei Hsu,Ignatia B. Van den Veyver,Ann M. Flenniken,Colin McKerlie,Stephen A. Murray,Lydia Teboul,Jason D. Heaney,Kevin C K Lloyd,Louise Lanoue,Robert Braun,Jacqueline K. White,Amie Creighton,Valerie Laurin,Ruolin Guo,Dawei Qu,Sara Wells,James Cleak,Rosie K. A. Bunton-Stasyshyn,Michelle Stewart,Jackie Harrisson,Jeremy Mason,Hamed Haseli Mashhadi,Helen Parkinson,Ann-Marie Mallon,John R. Seavitt,Angelina Gaspero,Uchechukwu Akoma,Audrey E. Christiansen,Sowmya Kalaga,Lance C. Keith,Melissa L. McElwee,Leeyean Wong,Tara L. Rasmussen,Uma Ramamurthy,K. Rajaya,Panitee Charoenrattanaruk,Qing Fan-Lan,Lauri G. Lintott,Ozge Danisment,Patricia Castellanos-Penton,Daniel Archer,Sara Johnson,Zsombor Szoke-Kovacs,Kevin A. Peterson,Leslie O. Goodwin,Ian C. Welsh,Kristina Palmer,Alana Luzzio,Cynthia Paige Carpenter,Coleen Kane,Jack Marcucci,Matthew Mckay,Crystal W. Burke,Audrie M. Seluke,Rachel Urban,J. Ambrose,Prabhu Arumugam,Roel P. J. Bevers,Marta Bleda,Freya Boardman-Pretty,Chris Boustred,Helen Brittain,Matthew A. Brown,Mark J. Caulfield,G. Chan,Greg Elgar,Adam Giess,John M. Griffin,Angela Hamblin,Shirley Henderson,Tim Hubbard,R. Jackson,L. J. Jones,Dalia Kasperaviciute,Melis Kayikci,Athanasios Kousathanas,L. Lahnstein,Sarah Leigh,I. Leong,J. F. López,Fiona Maleady-Crowe,Meriel McEntagart,Federico Minneci,Jonathan D. Mitchell,Loukas Moutsianas,M. Mueller,Nirupa Murugaesu,Anna C. Need,Peter O'Donovan,Christopher A. Odhams,Christine Patch,Mariana Buongermino Pereira,Daniel Perez-Gil,John Pullinger,T. Rahim,Augusto Rendon,Tim Rogers,Kevin Savage,K. Sawant,Richard T. Scott,Afshan Siddiq,A. Sieghart,Samuel C. Smith,Alona Sosinsky,Alexander Stuckey,Mélanie Tanguy,Ana Lisa Taylor Tavares,Ellen Thomas,Simon G. Thompson,Arianna Tucci,M. Welland,Eleanor Williams,K. Witkowska,S. Wood,Magdalena Zarowiecki,Damian Smedley +121 more
TL;DR: In this paper , the embryonic stage at which homozygous loss-of-function results in lethality in mice from the International Mouse Phenotyping Consortium, classifying the set of lethal genes into three windows of lethality: early, mid, or late gestation lethal.
Shear stress and platelet-induced tensile forces regulate ADAMTS13-localization within the platelet thrombus.
Yasuaki Shida,Laura L. Swystun,Christine Brown,Jeffrey Mewburn,Kate Nesbitt,Ozge Danisment,Jonathan Jacob Riches,Christine Hough,David Lillicrap +8 more
- 23 Mar 2019
TL;DR: The multimeric glycoprotein von Willebrand factor mediates platelet adhesion and aggregation at the site of vessel injury and is influenced by its multimer length which is regulated by the metalloprotease ADAMTS13.