Oscar Coll
University of Barcelona
15 Papers
149 Citations
Oscar Coll is an academic researcher from University of Barcelona. The author has contributed to research in topics: Nucleophile & Ring (chemistry). The author has an hindex of 7, co-authored 15 publications.
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Papers
General Access to Tacamine and Vinca‐Eburna Alkaloids through Tandem Non‐Biomimetic Oxidation of Dihydropyridines/Zn‐Mediated Radical Addition Processes − Unexpected Facial Selectivity of Flattened Cyclohexyl‐Type Radicals
TL;DR: In this paper, a general route to the eburnamine-vincamine and tacamine indole alkaloid groups has been developed and the key features of the synthetic strategy are the halocyclization of a dihydropyridine (a non-biomimetic oxidation of these compounds) and the radical addition of the resulting halo derivative to activated alkenes.
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Introduction of heteroatom-based substituents into 1,4-dihydropyridines by means of a halogen-mediated, oxidative protocol: diamination, sulfonylation, sulfinylation, bis-sulfanylation, and halo-phosphonylation processes
Rodolfo Lavilla,Rakesh Kumar,Oscar Coll,Carme Masdeu,Alessandro Spada,Joan Bosch,E. Espinosa,Elies Molins +7 more
TL;DR: The natural tendency of 1,4-dihydropyridines to undergo "biomimetic" oxidation to afford pyridinium salts can be switched off and, through the use of reagents that interact electrophilically with the enamine moiety present in the heterocyclic system, it is possible to promote alternative oxidations.
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Vicinal diamination of 1,4-dihydropyridines
TL;DR: In this article, the authors proposed a method for the synthesis of piperidine, pyrrolidine, morpholine, and piperazine derivatives using N-alkyl-1,4-dihydropyridines in the presence of secondary amines.
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