Orsolya Kréneisz
University of Connecticut
7 Papers
75 Citations
Orsolya Kréneisz is an academic researcher from University of Connecticut. The author has contributed to research in topics: Glibenclamide & Sulfonylurea receptor. The author has an hindex of 5, co-authored 7 publications.
Chat about Author
Papers
Astrocytes in the retrotrapezoid nucleus sense H+ by inhibition of a Kir4.1-Kir5.1-like current and may contribute to chemoreception by a purinergic mechanism.
TL;DR: itrate increased baseline activity and pH sensitivity of RTN neurons by a P2-receptor-dependent mechanism, suggesting that astrocytes may release ATP to activate RTN chemoreceptors and may provide an excitatory purinergic drive to pH-sensitive neurons.
139
Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan
Yih-Woei C. Fridell,Melissa Hoh,Orsolya Kréneisz,Suzanne Hosier,Chengyi Chang,Dane Scantling,Daniel K. Mulkey,Stephen L. Helfand +7 more
- 21 Jul 2009
TL;DR: A role for UCP in adult Drosophila IPCs is demonstrated in influencing systemic insulin signaling and longevity by a mechanism that may involve KATP channels.
74
Glucose increases activity and Ca2+ in insulin-producing cells of adult Drosophila.
TL;DR: These results provide the first detailed characterization of electrical properties of IPCs of adult Drosophila and suggest that these cells sense glucose by a mechanism similar to mammalian pancreatic &bgr; cells.
AMP-activated protein kinase inhibits TREK channels.
TL;DR: The results identify a novel modulation of TREK channels by AMPK and indicate that select residues in the C‐terminus of TREk are points of convergence for multiple signalling cascades including AMPK, PKA and PKC.
63
Current ideas on central chemoreception by neurons and glial cells in the retrotrapezoid nucleus
TL;DR: The defining characteristics of pH-sensitive neurons are summarized and potential contributions of pH/pH-sensitive glial cells as both a source of purinergic drive to pH- sensitive neurons and a modulator of vasculature tone are discussed.
22