Olle Matsson
Uppsala University
32 Papers
291 Citations
Olle Matsson is an academic researcher from Uppsala University. The author has contributed to research in topics: Kinetic isotope effect & Leaving group. The author has an hindex of 11, co-authored 32 publications. Previous affiliations of Olle Matsson include Lund University.
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Papers
Secondary deuterium kinetic isotope effects and transition state structure
TL;DR: The chapter demonstrates the ways in which secondary deuterium and tritium KIEs can be used to elucidate the mechanisms of reactions and determine the structure of their transition states.
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Nitrogen kinetic isotope effects for the monoamine oxidase B-catalyzed oxidation of benzylamine and (1,1-(2)H2)benzylamine: nitrogen rehybridization and CH bond cleavage are not concerted.
TL;DR: Nitrogen kinetic isotope effects for the oxidation of benzylamine by recombinant human monoamine oxidase B show that cleavage of the CH bond is not concerted with rehybridization of the nitrogen atom.
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The Mechanism of Base-Promoted HF Elimination from 4-Fluoro-4-(4‘-nitrophenyl)butan-2-one: A Multiple Isotope Effect Study Including the Leaving Group 18F/19F KIE
Per Ryberg,Olle Matsson +1 more
TL;DR: Leaving-group fluorine as well as the primary and secondary deuterium kinetic isotope effects (KIEs) have been determined for the base-promoted elimination of hydrogen fluoride from 4-fluoro-4-(4'-nitrophenyl)butan-2-one in aqueous solution.
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Solvent Dependent Leaving Group Fluorine Kinetic Isotope Effect in a Nucleophilic Aromatic Substitution Reaction
TL;DR: In this paper, the solvent dependence of the leaving group F KIE was investigated for the nucleophilic aromatic substitution reaction (SNAr) of 2,4-dinitrofluorobenzene with piperidine at 22 oC.
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The Mechanism of Base-Promoted HF Elimination from 4-Fluoro-4-(4-nitrophenyl)butan-2-one Is E1cB. Evidence from Double Isotopic Fractionation Experiments
Per Ryberg,Olle Matsson +1 more
TL;DR: Leaving-group fluorine and secondary deuterium multiple kinetic isotope effects (KIEs) have been determined for the base-promoted HF elimination from the 4-fluoro-4-(4'-nitrophenyl)-(1,1,2,3,3-3-(2)H(5))butan-2-one and this new data clearly demonstrates that the elimination proceeds via an E1cB mechanism.
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