Oliver J. Rando
University of Massachusetts Medical School
171 Papers
508 Citations
Oliver J. Rando is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Chromatin & Nucleosome. The author has an hindex of 65, co-authored 158 publications. Previous affiliations of Oliver J. Rando include Stanford University & Harvard University.
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Papers
Profiling of Pluripotency Factors in Single Cells and Early Embryos.
Sarah J. Hainer,Sarah J. Hainer,Ana Bošković,Kurtis N. McCannell,Oliver J. Rando,Thomas G. Fazzio +5 more
TL;DR: The cleavage under targets and release using nuclease (CUT&RUN) method is adapted to profile TFs in low cell numbers, including single cells and individual pre-implantation embryos, to enable interrogation of TF binding from rare cell populations of particular importance in development or disease.
174
Metabolic Inputs into the Epigenome.
Upasna Sharma,Oliver J. Rando +1 more
TL;DR: Interestingly, over the past decade multiple studies have shown that ancestral nutrition can alter the metabolic phenotype of offspring, raising the question of how metabolism regulates the epigenome of germ cells.
160
Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal
Rubing Zhao-Shea,Steven R. DeGroot,Liwang Liu,Markus Vallaster,Xue-Yan Pang,Qin Su,Guangping Gao,Oliver J. Rando,Gilles E. Martin,Olivier George,Paul D. Gardner,Andrew R. Tapper +11 more
TL;DR: It is shown that withdrawal-induced anxiety increases activity of neurons in the interpeduncular intermediate (IPI), a subregion of the interpinguncular nucleus (IPN), and increased CRF receptor signaling within a VTA-IPN-MHb circuit triggers anxiety during nicotine withdrawal.
Mechanisms Underlying Nucleosome Positioning In Vivo
Amanda L. Hughes,Oliver J. Rando +1 more
TL;DR: The factors impacting nucleosome positioning and the ways that nucleosomes can control the output of the genome are reviewed.
147
Transcriptome-wide Analysis of Roles for tRNA Modifications in Translational Regulation.
TL;DR: This data build on prior reports documenting translational upregulation of the nutrient-responsive transcription factor Gcn4 in response to numerous tRNA perturbations, and identify many additional translationally regulated mRNAs throughout the yeast genome.
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