Oliver J. Rando
University of Massachusetts Medical School
171 Papers
508 Citations
Oliver J. Rando is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Chromatin & Nucleosome. The author has an hindex of 65, co-authored 158 publications. Previous affiliations of Oliver J. Rando include Stanford University & Harvard University.
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Papers
LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo
Joanna W. Jachowicz,Xinyang Bing,Julien Pontabry,Ana Bošković,Oliver J. Rando,Maria-Elena Torres-Padilla +5 more
TL;DR: It is demonstrated that premature silencing of LINE-1 elements decreases chromatin accessibility, whereas prolonged activation prevents the gradual chromatin compaction that occurs naturally in developmental progression, suggesting that Line-1 functions primarily at the chromatin level.
345
Nucleosome positioning: how is it established, and why does it matter?
TL;DR: How nucleosomes positions are established, what effect nucleosome positioning has on control of gene expression, and touch on the correlations between chromatin packaging, sequence evolution, and the evolution of geneexpression programs are discussed.
334
Chromatin and Transcription in Yeast
Oliver J. Rando,Fred Winston +1 more
TL;DR: A review article summarizes the large body of yeast studies in this field of chromatin-remodeling factors and histone modification activities found during studies of Saccharomyces cerevisiae.
319
Daddy Issues: Paternal Effects on Phenotype
TL;DR: The once popular and then heretical idea that ancestral environment can affect the phenotype of future generations is coming back into vogue due to advances in the field of epigenetic inheritance.
296
Combinatorial complexity in chromatin structure and function: revisiting the histone code.
TL;DR: This review will focus on contrasting results of functional and localization studies finding minimal combinatorial complexity in histone modification patterns, and possible ways to reconcile these conflicting views.
294