Oliver J. Rando
University of Massachusetts Medical School
171 Papers
508 Citations
Oliver J. Rando is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Chromatin & Nucleosome. The author has an hindex of 65, co-authored 158 publications. Previous affiliations of Oliver J. Rando include Stanford University & Harvard University.
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Papers
Regulation of X-linked gene expression during early mouse development by Rlim
Feng Wang,JongDae Shin,JongDae Shin,Jeremy M. Shea,Jun Yu,Ana Bošković,Meg Byron,Xiaochun Zhu,Alex K. Shalek,Aviv Regev,Jeanne B. Lawrence,Eduardo M. Torres,Lihua Julie Zhu,Oliver J. Rando,Ingolf Bach +14 more
TL;DR: It is found that X/A upregulation is initiated in early male and female preimplantation embryos and crucial roles of Rlim for the maintenance of high Xist RNA levels, Xist clouds and X-silencing in female embryos at blastocyst stages are revealed.
Resolving the 3D landscape of transcription-linked mammalian chromatin folding
Tsung-Han S. Hsieh,Elena Slobodyanyuk,Anders S. Hansen,Claudia Cattoglio,Oliver J. Rando,Robert Tjian,Xavier Darzacq +6 more
TL;DR: This work uncovers the finer-scale genome organization that establishes novel functional links between chromatin folding and gene regulation and detects “two-start” zig-zag 30-nanometer chromatin fibers.
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Feedback Control of Set1 Protein Levels Is Important for Proper H3K4 Methylation Patterns
TL;DR: It is proposed that careful tuning of Set1 levels by regulated degradation is critical for the establishment and maintenance of proper H3K4 methylation patterns.
Chromatin structure in the genomics era
TL;DR: New genomics approaches to understanding chromatin structure in eukaryotes are reviewed, by enabling researchers to identify the coregulation patterns of thousands of genes.
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