Oliver J. Rando
University of Massachusetts Medical School
171 Papers
508 Citations
Oliver J. Rando is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Chromatin & Nucleosome. The author has an hindex of 65, co-authored 158 publications. Previous affiliations of Oliver J. Rando include Stanford University & Harvard University.
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Papers
The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
TL;DR: The ubiquitin-proteasome pathway has been shown to play an essential role in two proteolytic processes required for activation of the transcription factor NF-κB as discussed by the authors.
2.1K
Genome-scale identification of nucleosome positions in S. cerevisiae.
Guo-Cheng Yuan,Yuen-Jong Liu,Michael F. Dion,Michael D. Slack,Lani F. Wu,Steven J. Altschuler,Oliver J. Rando +6 more
TL;DR: The authors used a tiled microarray approach to identify at high resolution the translational positions of 2278 nucleosomes over 482 kilobases of Saccharomyces cerevisiae DNA.
1.2K
Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals
Upasna Sharma,Colin C. Conine,Jeremy M. Shea,Ana Bošković,Alan G. Derr,Xin Y. Bing,Clémence Belleannée,Alper Kucukural,Ryan W. Serra,Fengyun Sun,Lina Song,Benjamin R. Carone,Emiliano P. Ricci,Xin Zhiguo Li,Lucas Fauquier,Melissa J. Moore,Robert Sullivan,Craig C. Mello,Manuel Garber,Oliver J. Rando +19 more
TL;DR: The results shed light on sRNA biogenesis and its dietary regulation during posttesticular sperm maturation, and they also link tRNA fragments to regulation of endogenous retroelements active in the preimplantation embryo.
1.1K
Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals
Benjamin R. Carone,Lucas Fauquier,Naomi Habib,Jeremy M. Shea,Caroline E. Hart,Ruowang Li,Christoph Bock,Christoph Bock,Chengjian Li,Hongcang Gu,Phillip D. Zamore,Alexander Meissner,Alexander Meissner,Zhiping Weng,Hans A. Hofmann,Nir Friedman,Oliver J. Rando +16 more
TL;DR: It is indicated that parental diet can affect cholesterol and lipid metabolism in offspring and define a model system to study environmental reprogramming of the heritable epigenome.
1.1K
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors.
Jie Wang,Jiali Zhuang,Sowmya Iyer,Sowmya Iyer,Xinying Lin,Troy W. Whitfield,Melissa C. Greven,Brian G. Pierce,Xianjun Dong,Anshul Kundaje,Yong Cheng,Oliver J. Rando,Ewan Birney,Richard M. Myers,William Stafford Noble,Michael Snyder,Zhiping Weng +16 more
TL;DR: An integrative analysis centered around 457 ChIP-seq data sets on 119 human TFs generated by the ENCODE Consortium identified highly enriched sequence motifs in most data sets, revealing new motifs and validating known ones.