Olga Cano
Carlos III Health Institute
20 Papers
67 Citations
Olga Cano is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Antibody & Medicine. The author has an hindex of 9, co-authored 11 publications.
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Papers
Thermostability of the human respiratory syncytial virus fusion protein before and after activation: implications for the membrane-fusion mechanism.
M. Begoña Ruiz-Argüello,Diana Martín,Steve A. Wharton,Lesley J. Calder,Steve R. Martin,Olga Cano,Miguel Calero,Blanca García-Barreno,John J. Skehel,José A. Melero +9 more
TL;DR: The uncleaved and cleaved forms of may represent the pre- and post-active forms of RSV F protein, and their thermostability before and after proteolytic cleavage was examined, finding them equally resistant to heat denaturation.
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Recombinant sendai viruses expressing fusion proteins with two furin cleavage sites mimic the syncytial and receptor-independent infection properties of respiratory syncytial virus
TL;DR: Rec recombinant Sendai viruses (rSeV) that express mutant F proteins containing one or both FRSV cleavage sites are described, which mimicking the unique ability of RSV to fuse and infect cells in the absence of a separate attachment protein.
Chimeric Pneumoviridae fusion proteins as immunogens to induce cross-neutralizing antibody responses.
Eduardo Olmedillas,Olga Cano,Isidoro Martínez,Daniel Luque,María C. Terrón,Jason S. McLellan,José A. Melero,Vicente Mas +7 more
TL;DR: The results provide a proof of principle for chimeric fusion proteins as single immunogens that can induce cross‐neutralizing antibody and protective responses against more than one human pneumovirus.
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High level expression of soluble glycoproteins in the allantoic fluid of embryonated chicken eggs using a Sendai virus minigenome system
Teresa Corral,Lorena S. Ver,Geneviève Mottet,Olga Cano,Blanca García-Barreno,Lesley J. Calder,John J. Skehel,Laurent Roux,José A. Melero +8 more
TL;DR: The simplicity and economy of the Sendai minigenome system, together with the high yield achieved in the allantoic fluid of eggs, makes it an attractive method to express soluble glycoproteins aimed for structural studies.
Towards Control and Oversight of SARS‐CoV‐2 Diagnosis and Monitoring through Multiplexed Quantitative Electroanalytical Immune Response Biosensors
Rebeca M. Torrente-Rodríguez,Ana Montero-Calle,Clara San Bartolome,Olga Cano,M. Vázquez,Maria Iglesias-Caballero,Andrés Corral-Lugo,Michael J. McConnell,Mariona Pascal,Vicente Mas,José M. Pingarrón,Rodrigo Barderas,Susana Campuzano +12 more
TL;DR: The obtained results using N and in‐house expressed S ectodomains of five SARS‐CoV‐2 variants of concern allow identification of vulnerable populations from those with natural or acquired immunity, monitoring of infection, evaluation of vaccine efficiency, and even identification of the variant responsible for the infection.
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