Oleksandr Ekshyyan
LSU Health Sciences Center Shreveport
30 Papers
66 Citations
Oleksandr Ekshyyan is an academic researcher from LSU Health Sciences Center Shreveport. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Cancer. The author has an hindex of 13, co-authored 30 publications. Previous affiliations of Oleksandr Ekshyyan include Louisiana State University in Shreveport & Louisiana State University.
Chat about Author
Papers
Neuronal apoptosis in neurodegeneration.
TL;DR: The current review focuses on two major areas: the fundamentals of apoptosis, which includes elements of the apoptotic machinery, apoptosis inducers, and emerging concepts in apoptosis research, and apoptotic involvement in neurodegenerative disorders, neuroprotective treatment strategies/modalities.
229
Differential Effects of Superoxide Dismutase Isoform Expression on Hydroperoxide-induced Apoptosis in PC-12 Cells
TL;DR: A role for mitochondrial ROS in TBH-induced PC-12 apoptosis is supported that is attenuated by Mn-SOD overexpression and is independent of cellular GSH levelsper se.
131
Association between human papilloma virus/Epstein-Barr virus coinfection and oral carcinogenesis.
Ru Jiang,Ru Jiang,Oleksandr Ekshyyan,Tara Moore-Medlin,Xiaohua Rong,Sean Nathan,Xin Gu,Fleurette Abreo,Eben L. Rosenthal,Mingxia Shi,Joseph T. Guidry,Rona S. Scott,Lindsey M. Hutt-Fletcher,Cherie-Ann O. Nathan +13 more
TL;DR: There is a high prevalence of HPV/EBV infection and coinfection in BOT and tonsil cancers, possibly reflecting their origins in lymphoid-rich tissue.
Comparison of radiosensitizing effects of the mammalian target of rapamycin inhibitor CCI-779 to cisplatin in experimental models of head and neck squamous cell carcinoma
Oleksandr Ekshyyan,Youhua Rong,Xiaohua Rong,Kavita M. Pattani,Fleurette Abreo,Gloria Caldito,John Kai Siung Chang,Federico L. Ampil,Jonathan D. Glass,Cherie-Ann O. Nathan +9 more
TL;DR: Results pave the way for clinical trials using molecular targeted therapy with CCI-779 in combination with XRT for HNSCC treatment and show antitumor activity superior to conventional chemoradiotherapy with cisplatin.
78
Apoptosis in acute and chronic neurological disorders.
Oleksandr Ekshyyan,Tak Yee Aw +1 more
TL;DR: This review will focus on the general concepts of the current understanding of the apoptosis death machinery, its mediators and regulation, and the relationship between aberrant apoptosis and genesis of neurodegenerative disorders.
72