Olaf Ortmann
University of Regensburg
172 Papers
631 Citations
Olaf Ortmann is an academic researcher from University of Regensburg. The author has contributed to research in topics: Medicine & Breast cancer. The author has an hindex of 25, co-authored 110 publications. Previous affiliations of Olaf Ortmann include Caritas Hospital.
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Papers
A Randomized Trial Of Exemestane After Two To Three Years Of Tamoxifen Therapy In Postmenopausal Women With Primary Breast Cancer.
R. C. Coombes,Emma Hall,Lorna Gibson,Robert Paridaens,Jacek Jassem,Thierry Delozier,Stephen E. Jones,Isabel Alvarez,Gianfilippo Bertelli,Olaf Ortmann,Alan S. Coates,Emilio Bajetta,D. Dodwell,Robert E. Coleman,Lesley Fallowfield,Elizabeth Mickiewicz,Jens O. Andersen,Per Eystein Lønning,G. Cocconi,Alan L Stewart,N Stuart,Claire Snowdon,M. Carpentieri,Giorgio Massimini,Judith M Bliss +24 more
TL;DR: Exemestane therapy after two to three years ofTamoxifen therapy significantly improved disease-free survival as compared with the standard five years of tamoxIFen treatment.
Effect of Luteinizing Hormone–Releasing Hormone Agonist on Ovarian Function After Modern Adjuvant Breast Cancer Chemotherapy: The GBG 37 ZORO Study
Bernd Gerber,Gunter von Minckwitz,Heinrich Stehle,Toralf Reimer,Ricardo Felberbaum,Nikolai Maass,Dorothea Fischer,Harald Sommer,B. Conrad,Olaf Ortmann,Tanja Fehm,Mahdi Rezai,Keyur Mehta,Sibylle Loibl +13 more
TL;DR: Premenopausal patients with breast cancer receiving goserelin simultaneously with modern neoadjuvant chemotherapy did not experience statistically significantly less amenorrhea 6 months after end of chemotherapy compared with those receiving chemotherapy alone.
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Estrogen receptor {beta}1 exerts antitumoral effects on SK-OV-3 ovarian cancer cells.
TL;DR: It is demonstrated that ERbeta1, but not the exon-deleted isoforms tested exerts multiple antitumoral effects on SK-OV-3 ovarian cancer cells even in the absence of estradiol or functional ERalpha.
Estrogen Receptor beta Exerts Growth-Inhibitory Effects on Human Mammary Epithelial Cells.
TL;DR: The data suggest that ERβ exerts antiproliferative effects both on MCF-10A andMCF-7 cells in a ligand- and ERα-independent manner by regulation of p21/WAF or cyclin A2 gene expression.
Effects of a combined treatment with mTOR inhibitor RAD001 and tamoxifen in vitro on growth and apoptosis of human cancer cells
TL;DR: Combination treatment with RAD001 and 4-OH TAM in vitro exerts an additive antitumoral effect on ovarian cancer cells and MCF-7 breast cancer cells.
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