Octavio Ramilo
Ohio State University
252 Papers
1.8K Citations
Octavio Ramilo is an academic researcher from Ohio State University. The author has contributed to research in topics: Medicine & Virus. The author has an hindex of 58, co-authored 223 publications. Previous affiliations of Octavio Ramilo include University of Texas at Dallas & The Research Institute at Nationwide Children's Hospital.
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Papers
Infliximab Treatment of Intravenous Immunoglobulin–Resistant Kawasaki Disease
Jane C. Burns,Brookie M. Best,Asuncion Mejias,Lynn Mahony,David E Fixler,Hasan S. Jafri,Marian E. Melish,Mary Anne Jackson,Basim I. Asmar,David J. Lang,James D. Connor,Edmund V. Capparelli,Monica L. Keen,Khalid Mamun,Gregory F. Keenan,Octavio Ramilo +15 more
TL;DR: Both infliximab and a second IVIG infusion were safe and well tolerated in the subjects with KD who were resistant to standard IVIG treatment.
Respiratory syncytial virus persistence in the lungs correlates with airway hyperreactivity in the mouse model.
Dora Estripeaut,Juan Pablo Torres,Cynthia S. Somers,Claudia Tagliabue,Shama Khokhar,Vijay Bhoj,Steve M. Grube,Aneta Wozniakowski,Ana M. Gomez,Octavio Ramilo,Hasan S. Jafri,Asuncion Mejias +11 more
TL;DR: Infection with live RSV induced acute and chronic airway disease that was associated with a predominantly Th-1 immune response and RSV RNA persistence that significantly correlated with pulmonary function abnormalities.
Comparative Effects of Two Neutralizing Anti-Respiratory Syncytial Virus (RSV) Monoclonal Antibodies in the RSV Murine Model: Time versus Potency
Asuncion Mejias,Susana Chavez-Bueno,Ana María Ríos,Mónica Fonseca Aten,Brett Raynor,Estrella Peromingo,Perla Soni,Kurt Olsen,Peter A. Kiener,Ana M. Gomez,Hasan S. Jafri,Octavio Ramilo +11 more
TL;DR: MEDI-524 was superior to palivizumab on several outcome variables of RSV disease assessed in the mouse model: viral replication, inflammatory and clinical markers of acute disease severity, and long-term pulmonary abnormalities.
Severe SARS-CoV-2 disease in the context of a NF-κB2 loss-of-function pathogenic variant.
Roshini S. Abraham,Joanna M. Marshall,Hye Sun Kuehn,Cesar M. Rueda,Amber Gibbs,Will Guider,Claire Stewart,Sergio D. Rosenzweig,Huanyu Wang,Sophonie Jean,Mark E. Peeples,Mark E. Peeples,Tiffany King,Tiffany King,W. Garrett Hunt,W. Garrett Hunt,Jonathan R. Honegger,Jonathan R. Honegger,Octavio Ramilo,Octavio Ramilo,Peter J. Mustillo,Peter J. Mustillo,Asuncion Mejias,Asuncion Mejias,Monica I Ardura,Monica I Ardura,Masako Shimamura,Masako Shimamura +27 more
TL;DR: The functional consequence and immunological phenotype of a novel NFKB2 LOF variant in a 17y old male patient and the clinical management of SARS-CoV-2 infection in this context are evaluated.
Differences in SARS-CoV-2 Clinical Manifestations and Disease Severity in Children and Adolescents by Infecting Variant
Ana Maria Quintero,Mary Therese Eisner,Rouba Sayegh,Tori Wright,Octavio Ramilo,Amy Leber,Huan Wang,Asuncion Mejias +7 more
TL;DR: Inpatients with acute Delta and Omicron infections had lower SARS-CoV-2 cycle threshold values and more frequent fever and respiratory symptoms than those with nonvariant strain infections and were independently associated with worse clinical outcomes, irrespective of the infecting variant.