Nuria Flames
Spanish National Research Council
32 Papers
129 Citations
Nuria Flames is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Transcription factor & Biology. The author has an hindex of 20, co-authored 26 publications. Previous affiliations of Nuria Flames include University of Valencia & Universidad Miguel Hernández de Elche.
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Papers
Adult Ependymal Cells Are Postmitotic and Are Derived from Radial Glial Cells during Embryogenesis
Nathalie Spassky,Florian T. Merkle,Nuria Flames,Anthony D. Tramontin,José Manuel García-Verdugo,Arturo Alvarez-Buylla +5 more
TL;DR: The results indicate that ependymal cells are born in the embryonic and early postnatal brain and that they do not divide after differentiation, which strongly suggests that these cells do not function as neural stem cells in the adult.
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Tangential Neuronal Migration Controls Axon Guidance: A Role for Neuregulin-1 in Thalamocortical Axon Navigation
Guillermina López-Bendito,Aline Cautinat,Juan Antonio Sánchez,Franck Bielle,Nuria Flames,Alistair N. Garratt,David A. Talmage,Lorna W. Role,Patrick Charnay,Oscar Marín,Sonia Garel +10 more
TL;DR: It is shown that the development of the thalamocortical projection, one of the most prominent tracts in the mammalian brain, depends on the early tangential migration of a population of neurons derived from the ventral telencephalon.
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The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain.
Yangu Zhao,Oscar Marín,Edit Hermesz,Aaron Powell,Nuria Flames,Miklós Palkovits,John L.R. Rubenstein,Heiner Westphal +7 more
TL;DR: Genetic evidence supporting an important role for Lhx8 in development of cholinergic neurons in the forebrain is provided, as indicated by a presence of cells expressing a truncated Lx8 mRNA and mRNA of the homeobox gene Gbx1.
Developmental mechanisms underlying the generation of cortical interneuron diversity.
Nuria Flames,Oscar Marín +1 more
TL;DR: Recent data on how the large variety of distinct classes of cortical interneurons may arise during development are reviewed to help understand their role as integrative and synchronizing elements in cortical function.
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Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl‐xL in successful aging
Consuelo Borrás,Kheira M. Abdelaziz,Juan Gambini,Eva Serna,Marta Inglés,Mónica De la Fuente,Idoia Garcia,Ander Matheu,Paula Sanchis,Angel Belenguer,Alessandra Errigo,Juan A. Avellana,Ana Barettino,Carla Lloret-Fernandez,Nuria Flames,Gianni Pes,Leocadio Rodríguez-Mañas,Jose Viña +17 more
- 28 Oct 2016
TL;DR: Results show that mRNA expression in centenarians is unique and reveals that BcL- xL plays an important role in exceptional aging, and shows a significant increase in mean and maximal life span.
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