Noreen Sheehy
University College Dublin
37 Papers
308 Citations
Noreen Sheehy is an academic researcher from University College Dublin. The author has contributed to research in topics: Virus & Transactivation. The author has an hindex of 14, co-authored 35 publications.
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Papers
In vitro nuclear interactome of the HIV-1 Tat protein.
Virginie Gautier,Lili Gu,Niaobh O'Donoghue,Stephen R. Pennington,Noreen Sheehy,William W. Hall +5 more
TL;DR: The in vitro Tat nuclear interactome is completed and its modular network properties and particularly those involved in the coordination of gene expression by Tat are highlighted and will provide a framework to further advance the understanding of the mechanisms of HIV-1 proviral gene silencing and activation.
Concurrent evolution of regions of the envelope and polymerase genes of human immunodeficiency virus type 1 observed during zidovudine (AZT) therapy
TL;DR: Phylogenetic analyses showed that a reduction in genetic heterogeneity of the env regions of viruses present in the proviral blood population occurred during therapy, and this coincided with an increased pol gene heterogeneity.
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High rate of human T lymphotropic virus type IIa infection in HIV type 1-infected intravenous drug abusers in Ireland
John Egan,Bronagh O'Leary,Martha J. Lewis,Fiona Mulcahy,Noreen Sheehy,Hideki Hasegawa,Fidelma Fitzpatrick,John J. O'Connor,Joan O'Riordan,William W. Hall +9 more
TL;DR: Serological and molecular analyses of a cohort of HIV-1-infected intravenous drug abusers in Dublin, Ireland have demonstrated that 15 of 103 (14.6%) were infected with HTLV-II, which is the highest infection rate yet recorded for any European country.
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Differentiation of Chlamydia psittaci and C. pecorum strains by species-specific PCR.
TL;DR: PCR primers were designed to allow the specific amplification of DNA extracted from C. psittaci and C. pecorum strains of ovine and bovine origins and were in agreement with those obtained from AluI restriction enzyme analysis of DNA amplified from corresponding strains by PCR.
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Comparison of CREB- and NF-κB-mediated transactivation by human T lymphotropic virus type II (HTLV-II) and type I (HTLV-I) tax proteins
Martha J. Lewis,Martha J. Lewis,Noreen Sheehy,Marco Salemi,Anne-Mieke Vandamme,William W. Hall +5 more
TL;DR: These studies demonstrate that with the exception of some HTLV-IIA subtypes there are no significant differences in Tax transactivation via the CREB and NF-kappaB pathways between the two viruses and suggest that theHTLV-II Tax may have a pathogenic potential equivalent to that of HTLV -I.
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