Nobuyoshi Arima
Kyoto University
49 Papers
461 Citations
Nobuyoshi Arima is an academic researcher from Kyoto University. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 13, co-authored 42 publications.
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Papers
Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling.
Nobuyoshi Arima,Masanori Kamio,Kazunori Imada,Toshiyuki Hori,Toshio Hattori,Mitsuru Tsudo,Minoru Okuma,Takashi Uchiyama +7 more
TL;DR: It is considered that another protein whose molecular mass is approximately 65 kD is functionally important in IL-2 binding and subsequent signal transduction and may be the third component ofIL-2R.
Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia.
Michiyuki Maeda,Nobuyoshi Arima,Y Daitoku,M Kashihara,H Okamoto,T Uchiyama,K Shirono,Masao Matsuoka,Toshio Hattori,Kiyoshi Takatsuki +9 more
TL;DR: Evidence is provided for the IL-2- dependent proliferation of leukemic cells in some ATL patients by clonality analysis based on T cell receptor gene rearrangement profiles and the site of HTLV-I provirus integration.
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Single intra-arterial injection of mesenchymal stromal cells for treatment of steroid-refractory acute graft-versus-host disease: a pilot study.
Nobuyoshi Arima,Fumiaki Nakamura,Akiko Fukunaga,Hirokazu Hirata,Hiroko Machida,Shigene Kouno,Hajime Ohgushi +6 more
TL;DR: A single local arterial MSC injection was unable to save these patients' lives and so might not be more effective than multiple systemic intravenous M SC injection, and additional strategies are required to develop appropriate methods for using MSC to achieve extended remission of GvHD.
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Extragastric mucosa-associated lymphoid tissue lymphoma showing the regression by Helicobacter pylori eradication therapy.
Nobuyoshi Arima,Mitsuru Tsudo +1 more
TL;DR: Although H. pylori organisms were not detected in the lymphoma tissue by polymerase chain reaction (PCR), it might be implicated in the pathogenesis of extragastric MALT lymphomas.
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Role of α chain – IL-2 complex in the formation of the ternary complex of IL-2 and high-affinity IL-2 receptor
Masanori Kamio,Takashi Uchiyama,Nobuyoshi Arima,Katsuhiko Itoh,Takayuki Ishikawa,Toshiyuki Hori,Haruto Uchino +6 more
TL;DR: Using anti-Tac and 2R-B antibodies, it was strongly suggested that alpha chain-IL-2 complex has a key role in the formation of the ternary complex of IL-2 and high-affinity IL- 2 receptor.
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