Nobuo Koizumi
National Institutes of Health
106 Papers
404 Citations
Nobuo Koizumi is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Leptospira & Leptospirosis. The author has an hindex of 26, co-authored 93 publications.
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Papers
Prevalence of Leptospira spp. in the kidneys of wild boars and deer in Japan.
TL;DR: There was no annual change in the prevalence of positive animals during the investigation period and the Leptospira species harbored by these animals were deduced to be L. interrogans and L. borgpetersenii.
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Molecular epidemiology of Leptospira interrogans in Rattus norvegicus in Hanoi, Vietnam.
Nobuo Koizumi,Kozue Miura,Yu Sanai,Taichiro Takemura,Trang T. H. Ung,Thanh Thi Le,Kazuhiro Hirayama,Futoshi Hasebe,Hang Le Khanh Nguyen,Phuong Vu Mai Hoang,Cam Nhat Nguyen,Tuan Minh Khong,Mai Thi Quynh Le,Ha Thi Thu Hoang,Makoto Ohnishi +14 more
TL;DR: A high prevalence rate of L. interrogans among R. norvegicus in Hanoi, Vietnam is revealed, indicating a potential risk of rat-borne leptospirosis in the area and demonstrating that molecular detection is crucial in facilitating the accurate determination of reservoir animals.
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An attenuated Shigella mutant lacking the RNA-binding protein Hfq provides cross-protection against Shigella strains of broad serotype.
Jiro Mitobe,Ritam Sinha,Soma Mitra,Dhrubajyoti Nag,Noriko Saito,Ken Shimuta,Nobuo Koizumi,Hemanta Koley +7 more
TL;DR: Immunization with a mutant of Shigella flexneri 2a protected guinea pigs against subsequent infection by S. dysenteriae type 1 and S. sonnei strains, and vaccinated in the left eye showed fewer symptoms upon subsequent challenge via the right eye, and even survived subsequent intestinal challenge.
•Journal Article
Serological investigation of Leptospira infection and its circulation in one intensive-type water buffalo farm in the Philippines.
Marvin A. Villanueva,Claro N. Mingala,Nina G. Gloriani,Yasutake Yanagihara,Norikazu Isoda,Chie Nakajima,Yasuhiko Suzuki,Nobuo Koizumi +7 more
TL;DR: Leptospira infection was found associated with age and animal grouping, highlighting the impact of management in the persistence of leptospirosis at intensive-type buffalo farm settings in the Philippines.
Molecular and serological epidemiology of Leptospira infection in cats in Okinawa Island, Japan.
TL;DR: In this article, the authors used microscopic agglutination test and nested PCR to detect leptospirosis in cats in Okinawa Prefecture, Japan, and found that most seropositive cats had antibodies against the serogroup Javanica and that cats excreted L. borgpetersenii in the urine after infection.