Nobuko Iwata
Kobe University
21 Papers
269 Citations
Nobuko Iwata is an academic researcher from Kobe University. The author has contributed to research in topics: Receptor & Gastrin. The author has an hindex of 11, co-authored 19 publications.
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Papers
Expression of a kinase-defective Eph-like receptor in the normal human brain.
Hiroshi Matsuoka,Nobuko Iwata,Mitsuhiro Ito,Manabu Shimoyama,Aki Nagata,Kazuo Chihara,Setsuo Takai,Toshimitsu Matsui +7 more
TL;DR: HEP is the first description of a kinase-defective Eph-family protein expressed abundantly in normal human tissues and was expressed in the human brain as much as in CHO-K1 cells transfected with a HEP cDNA expression vector.
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Autocrine Loop Through Cholecystokinin-B/Gastrin Receptors Involved in Growth of Human Leukemia Cells
Nobuko Iwata,Tohru Murayama,Yoshinobu Matsumori,Mitsuhiro Ito,Aki Nagata,Taizo Taniguchi,Kazuo Chihara,Yoshinobu Matsuo,Jun Minowada,Toshimitsu Matsui +9 more
TL;DR: The results suggest that growth of human leukemia cells is promoted by an autocrine mechanism through the CCK-B/gastrin receptors.
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T-cell-specific expression of kinase-defective Eph-family receptor protein, EphB6 in normal as well as transformed hematopoietic cells.
Manabu Shimoyama,Hiroshi Matsuoka,Akira Tamekane,Mitsuhiro Ito,Nobuko Iwata,Ryuichi Inoue,Kazuo Chihara,Akiko Furuya,Nobuo Hanai,Toshimitsu Matsui +9 more
TL;DR: Results suggest that EphB6 expression is regulated in T-cell development, and prominent expression of E phB6 protein was demonstrated in CD4+CD8+ double-positive mouse thymocytes.
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•Journal Article
Functional characterization of two cholecystokinin-B/gastrin receptor isoforms: a preferential splice donor site in the human receptor gene.
TL;DR: Results suggest a species-specific dominant splice donor site in exon 4 of the human receptor gene, which is encoded by a single gene composed of five exons and spanning over 10 kilobases on human chromosome 11p 15.5-->15.4.
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•Journal Article
Cholecystokinin-B/Gastrin Receptor: A Novel Molecular Probe for Human Small Cell Lung Cancer
Yoshinobu Matsumori,Nobuyuki Katakami,Mitsuhiro Ito,Taizo Taniguchi,Nobuko Iwata,Tomoaki Takaishi,Kazuo Chihara,Toshimitsu Matsui +7 more
TL;DR: In this article, the cholecystokinin-B/gastrin receptor has been demonstrated to provide a novel molecular marker for the diagnosis of small cell lung cancer by using biopsy specimens.
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