Noboru Taniguchi
Kanazawa University
97 Papers
1.8K Citations
Noboru Taniguchi is an academic researcher from Kanazawa University. The author has contributed to research in topics: Interleukin 21 & T cell. The author has an hindex of 36, co-authored 97 publications.
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Papers
•Journal Article
Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.
Toshio Miyawaki,Takahiro Uehara,Ryutaro Nibu,Takao Tsuji,Akihiro Yachie,Shin Yonehara,Noboru Taniguchi +6 more
TL;DR: In contrast to Fas-expressing cultured cell lines, viability of in vitro stimulated T and B cells as well as freshly isolated CD45RO+ T cells was not significantly changed after the treatment with anti-Fas mAb, indicating that additional cellular conditions to Fas expression might be required for anti-fas-induced cell death.
520
Apoptotic cell death of primed CD45RO+ T lymphocytes in Epstein-Barr virus-induced infectious mononucleosis.
Takahiro Uehara,Toshio Miyawaki,Kazuhide Ohta,Yohichi Tamaru,T Yokoi,Shinobu Nakamura,Noboru Taniguchi +6 more
TL;DR: The studies suggest the programmed cell death of peripheral mature T cells as a mechanism of antigen-driven selection in acute IM as well as some cytokines such as interleukin-2, IL-5, and IL-6 could rescue IM T cells from apoptotic cell death.
212
•Journal Article
The acute phase nature of interleukin 6: studies in Kawasaki disease and other febrile illnesses.
Yasuhisa Ueno,N Takano,Hirokazu Kanegane,T Yokoi,Akihiro Yachie,Toshio Miyawaki,Noboru Taniguchi +6 more
TL;DR: Serum IL-6 activity correlated with serum concentrations of some acute phase proteins (APP), such as C-reactive protein, haptoglobin and alpha 1-acid glycoprotein, implying its role for modulating induction of APP in vivo.
138
Novel Fas (CD95/APO-1) mutations in infants with a lymphoproliferative disorder.
Yoshihito Kasahara,Taizo Wada,Yo Niida,Akihiro Yachie,Hidetoshi Seki,Yasushi Ishida,Tsuyoshi Sakai,Fumitomo Koizumi,Shoichi Koizumi,Toshio Miyawaki,Noboru Taniguchi +10 more
TL;DR: The results suggest that Fas-mediated apoptosis plays a pivotal role in immunological homeostasis in vivo, especially regarding clonal deletion of immune cells in humans.
108
•Journal Article
Cyclosporin A does not prevent expression of Tac antigen, a probable TCGF receptor molecule, on mitogen-stimulated human T cells.
TL;DR: Evidence is presented that CsA might not prevent the expression of probable functional receptor sites for TCGF in mitogen-dependent activation of human T cells, and the functional properties of activated T cells might be correlated with their ability to express Tac antigen.
105