Niraj K. Nirala
University of Massachusetts Medical School
17 Papers
14 Citations
Niraj K. Nirala is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Biology & Stem cell. The author has an hindex of 9, co-authored 14 publications. Previous affiliations of Niraj K. Nirala include Hamdard University & Saint Louis University.
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Papers
•Journal Article
Expression of a rice chitinase gene enhances antifungal potential in transgenic grapevine ( Vitis vinifera L.)
TL;DR: To enhance the antifungal potential of grapevine, transgenic plants were generated by transferring rice chitinase gene under a maize-ubiquitin promoter along with its first intron into the leaf disc-induced somatic embryos via Agrobacterium mediated transformation.
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Survival Response to Increased Ceramide Involves Metabolic Adaptation through Novel Regulators of Glycolysis and Lipolysis
Niraj K. Nirala,Motiur Rahman,Stanley M. Walls,Alka Singh,Lihua Julie Zhu,Takeshi Bamba,Eiichiro Fukusaki,Sargur Madabushi Srideshikan,Greg L. Harris,Y. Tony Ip,Rolf Bodmer,Usha Acharya +11 more
TL;DR: It is demonstrated here that the AKT/FOXO pathway regulates survival in increased ceramide environment by metabolic adaptation involving changes in glycolysis and lipolysis through novel downstream targets and develops cardiac dysfunction with age, likely reflecting the high energy requirement of a well-functioning heart.
•Journal Article
Encapsulated somatic embryos of grape ( Vitis vinifera L.): An efficient way for storage and propagation of pathogen-free plant material
TL;DR: Cotyledonary-stage somatic embryos originating from leaf explants of grape ( Vitis vinifera L.) cv were encapsulated individually in 2 % alginate gel and normally developed plantlets regenerated from ESEs were successfully adapted to soil.
Oncogenic Pathways and Loss of the Rab11 GTPase Synergize To Alter Metabolism in Drosophila.
Yingchao Nie,Shiyan Yu,Qi Li,Niraj K. Nirala,Alla Amcheslavsky,Yvonne J. K. Edwards,Patrick W Shum,Zhong Jiang,Wei Wang,Biliang Zhang,Nan Gao,Y. Tony Ip +11 more
TL;DR: It is found that loss of Rab11 can lead to three changes that may relate to cancer progression, including the disruption of enterocyte polarity based on staining of the FERM domain protein Coracle, and an increased proliferation due to an increased expression of the JAK-STAT pathway ligand Upd3.
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Overexpression of odc (ornithine decarboxylase) in Datura innoxia enhances the yield of scopolamine
TL;DR: The introduction of mouse odc gene of polyamine biosynthesis pathway which is also the primary pathway of tropane alkaloids in Datura innoxia is reported, leading to higher accumulation of scopolamine in transgenic plants.
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