Ningning Xu
University of Alabama at Birmingham
16 Papers
27 Citations
Ningning Xu is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Mitochondrion & Chinese hamster ovary cell. The author has an hindex of 8, co-authored 15 publications. Previous affiliations of Ningning Xu include University of Alabama.
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Papers
Process engineering of cellulosic n-butanol production from corn-based biomass using Clostridium cellulovorans
Jianfa Ou,Ningning Xu,Patrick Ernst,Chao Ma,Meredith Bush,KahYong Goh,Jingbo Zhao,Lufang Zhou,Shang-Tian Yang,Xiaoguang Liu +9 more
TL;DR: The fermentation process engineering of C. cellulovorans enabled a high butanol production directly from agricultural residues, showing that better cell growth and a higher concentration of n -butanol were produced from corn cob that was pretreated with sodium hydroxide in CBP.
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High butanol production by regulating carbon, redox and energy in Clostridia
TL;DR: This article systematically review the host cell engineering of Clostridia, focusing on various strategies to rebalance metabolic flux to achieve a high butanol production by regulating the metabolism of carbon, redox or energy.
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Rebalancing Redox to Improve Biobutanol Production by Clostridium tyrobutyricum
TL;DR: It is demonstrated that the redox engineering in C. tyrobutyricum could greatly increase butanol production by rebalancing redox.
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•Journal Article
Abstract 24059: Optogenetic-induced Mitochondrial Membrane Potential Depolarization and Targeting Cell Death
Patrick Ernst,Ningning Xu,KahYong Goh,Brian O'Rourke,Jianyi Zhang,Margaret X Liu,Lufang Zhou +6 more
TL;DR: A new generation optogenetic-based technique for targeting mitochondrial depolarization with light is developed and can be used to study the mechanisms how a change of mitochondrial membrane permeability influences cell and organ functions.
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Precisely control mitochondrial membrane potential with light to manipulate cell fate decisions
Patrick Ernst,Ningning Xu,Jiajia Song,Jing Qu,Herbert Chen,Matthew S. Goldberg,Jianyi Jay Zhang,Brian O'Rourke,Xiaoguang Liu,Lufang Zhou +9 more
TL;DR: It is shown that optogenetic-mediated mitochondrial depolarization can be well-controlled to differentially influence the fate of cells expressing mitochondrial ChR2: while mild, transient light illumination elicits cytoprotective effect, moderate, sustained light illumination induces apoptotic cell death.
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