Ning Wang
Karolinska University Hospital
15 Papers
129 Citations
Ning Wang is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Primary immunodeficiency & Medicine. The author has an hindex of 11, co-authored 13 publications.
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Papers
Neonatal screening for severe primary immunodeficiency diseases using high-throughput triplex real-time PCR
Stephan Borte,Ulrika von Döbeln,Anders Fasth,Ning Wang,Magdalena Janzi,Jacek Winiarski,Ulrich Sack,Qiang Pan-Hammarström,Michael Borte,Lennart Hammarström +9 more
TL;DR: Simultaneous measurement of TREC and KREC copy numbers in Guthrie card samples readily identified patients with SCID, XLA, ataxia-telangiectasia and Nijmegen-breakage-syndrome and thus facilitates effective newborn screening for severe immunodeficiency syndromes characterized by the absence of T or B cells.
215
Selective IgA Deficiency in Autoimmune Diseases
Ning Wang,Nan Shen,Timothy J. Vyse,Vidya Anand,Iva Gunnarson,Gunnar Sturfelt,Solbritt Rantapää-Dahlqvist,Kerstin Elvin,Lennart Truedsson,Bengt Andersson,Charlotte Dahle,Eva Örtqvist,Peter K. Gregersen,Timothy W. Behrens,Lennart Hammarström +14 more
TL;DR: Evidence is presented for a shared genetic predisposition between Graves disease, systemic lupus erythematosus, type 1 diabetes, celiac disease, myasthenia gravis, and rheumatoid arthritis on the basis of both large-scale screening results and literature data.
208
Novel mutations in TNFRSF7/CD27: Clinical, immunologic, and genetic characterization of human CD27 deficiency
Omar K. Alkhairy,Omar K. Alkhairy,Ruy Perez-Becker,Gertjan J. Driessen,Hassan Abolhassani,Hassan Abolhassani,Joris M. van Montfrans,Stephan Borte,Stephan Borte,Sharon Choo,Ning Wang,Kiki Tesselaar,Mingyan Fang,Kirsten Bienemann,Kaan Boztug,Ana Daneva,Francoise Mechinaud,Thomas Wiesel,Christian Becker,Gregor Dückers,Kathrin Siepermann,Menno C. van Zelm,Nima Rezaei,Mirjam van der Burg,Asghar Aghamohammadi,Markus G. Seidel,Markus G. Seidel,Tim Niehues,Lennart Hammarström +28 more
TL;DR: CD27 deficiency is potentially fatal and should be excluded in all cases of severe EBV infections to minimize diagnostic delay and flow cytometric immunophenotyping offers a reliable initial test for CD27 deficiency.
125
IgA deficiency: what is new?
Ning Wang,Lennart Hammarström +1 more
TL;DR: IgAD is the most common primary immunodeficiency in the Western world with a prevalence of approximately 1 : 600 in the general population and appears to be a polygenic disorder and several of the genes involved have recently been identified.
85
High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci associated with selective IgA deficiency.
Ricardo C. Ferreira,Qiang Pan-Hammarström,Robert R. Graham,Gumersindo Fontán,Annette Lee,Ward Ortmann,Ning Wang,Elena Urcelay,Miguel Fernández-Arquero,Concepción Núñez,Gudmundur H. Jorgensen,Bjorn R. Ludviksson,Sinikka Koskinen,Katri Haimila,Leonid Padyukov,Peter K. Gregersen,Lennart Hammarström,Timothy W. Behrens +17 more
TL;DR: Despite the strong population-specific frequencies of HLA alleles, a remarkable conservation of these effects regardless of the ethnic background is found, which supports the use of large multi-ethnic populations to characterize shared genetic association signals in the HLA region.