Ning Ning
University of Michigan
5 Papers
1 Citations
Ning Ning is an academic researcher from University of Michigan. The author has contributed to research in topics: Cancer stem cell & Cancer. The author has an hindex of 3, co-authored 5 publications. Previous affiliations of Ning Ning include Chinese PLA General Hospital.
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Papers
Cancer stem cell vaccination confers significant antitumor immunity
Ning Ning,Qin Pan,Qin Pan,Fang Zheng,Fang Zheng,Seagal Teitz-Tennenbaum,Martin Egenti,Ji Yet,Mu Li,Christophe Ginestier,Max S. Wicha,Jeffrey S. Moyer,Mark E. Prince,Yingxin Xu,Xiao-Lian Zhang,Shiang Huang,Alfred E. Chang,Qiao Li +17 more
TL;DR: Mechanistic investigations established that CSC-primed antibodies and T cells were capable of selective targeting CSCs and conferring antitumor immunity, providing a rationale for a new type of cancer immunotherapy based on the development of CSC vaccines that can specifically target C SCs.
Abstract 3322: Protective antitumor immunity induced by ALDEFLUOR+ enriched cancer stem cells
Ning Ning,Seagal Teitz-Tennenbaum,Ji Yet,Jeffrey S. Moyer,Christophe Ginestier,Max S. Wicha,Yingxin Xu,Alfred E. Chang,Qiao Li +8 more
TL;DR: It is hypothesized that cancer stem cell (CSC)-enriched populations in murine models may induce immunity specifically targeting CSCs, and protective antitumor responses induced by vaccination with dendritic cells pulsed with the lysate of ALDEFLUOR+ D5 cells in the syngeneic immunocompetent host are evaluated.
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Immunologic Approaches to Targeting Cancer Stem Cells
Qin Pan,Qin Pan,Qiao Li,Ning Ning,Ning Ning,Yingxin Xu,Alfred E. Chang,Max S. Wicha +7 more
- 01 Jan 2015
TL;DR: Targeting the tumor microenvironment, e.g., IL-6 neutralization or IL- 6R blockade, or interrupting the CXCR1/IL-8 interaction may provide novel strategies to enhance immunological targeting of cancer stem cells by T cell and cancer stem cell vaccines.
Adoptive Transfer of Tumor Reactive B Cells Confers Host T-Cell Immunity and Tumor Regression
Qiao Li,Xiang-Ming Lao,Xiang-Ming Lao,Qin Pan,Qin Pan,Ning Ning,Ji Yet,Yingxin Xu,Shengping Li,Alfred E. Chang +9 more
TL;DR: It is found that appropriately primed B cells can mediate tumor regression by itself and confers host T-cell antitumor immunity, and effector B cellsCan serve as a useful adjunct in adoptive T- cell therapy.
Concise Review: Targeting Cancer Stem Cells Using Immunologic Approaches
Qin Pan,Qiao Li,Shuang Liu,Ning Ning,Xiao-Lian Zhang,Yingxin Xu,Alfred E. Chang,Max S. Wicha +7 more
TL;DR: Targeting the tumor microenvironment, such as interrupting the immune cell, for example, myeloid‐derived suppressor cells, and cytokines, as well as the immune checkpoint (PD1/PDL1, etc.) may provide additional novel strategies to enhance the immunological targeting of CSCs.