Ning Li
Qingdao University
10 Papers
11 Citations
Ning Li is an academic researcher from Qingdao University. The author has contributed to research in topics: Apoptosis & Cell culture. The author has an hindex of 4, co-authored 10 publications.
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Papers
Dysfunction of chaperone-mediated autophagy in human diseases.
TL;DR: Chaperone-mediated autophagy (CMA), one of the degradation pathways of proteins, is highly selective to substrates that have KFERQ-like motif as discussed by the authors, which plays an important role in regulating glucose and lipid metabolism, transcription, DNA reparation, cell cycle, cellular response to stress and consequently, regulating many agingassociated human diseases.
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TIM-3 blockade combined with bispecific antibody MT110 enhances the anti-tumor effect of γδ T cells
Qingming Guo,Peng Zhao,Zhen Zhang,Jinyu Zhang,Zheng Zhang,Yanan Hua,Bin Han,Ning Li,Xiaowen Zhao,Lin Hou +9 more
TL;DR: It is found that the immune checkpoint T-cell immunoglobulin domain and mucin domain 3 (TIM-3) were up-regulated significantly on γδ T cells during their ex vivo expansion and this up-regulation contributed to the dysfunction of γ Δ T cells.
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TMEM166 inhibits cell proliferation, migration and invasion in hepatocellular carcinoma via upregulating TP53
Jiejie Yang,Bin Wang,Qian Xu,Yuling Yang,Lin Hou,Kan Yin,Qingming Guo,Yanan Hua,Li Zhang,Yixuan Li,Jinyu Zhang,Ning Li +11 more
TL;DR: The first comprehensive analysis of the role of TMEM166 in HCC suggests it is a potential target for the treatment of HCC and displays a fine anti-tumor activity on HCC cells involving a mechanism of upregulating TP53.
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Isatin inhibits the invasion and metastasis of SH‑SY5Y neuroblastoma cells in vitro and in vivo.
Yanan Hua,Na Zhou,Jinyu Zhang,Zheng Zhang,Ning Li,Jun Wang,Wenxiang Zheng,Xue Li,Fangling Wang,Li Zhang,Lin Hou +10 more
TL;DR: It is reported that isatin significantly inhibited neuroblastoma cell proliferation, invasion and migration in vitro in a dose‑dependent manner, and distant metastasis in tumor‑bearing mice, indicating its potential as a candidate drug as well as an adjuvant for treating metastatic Neuroblastoma.
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•Journal Article
Isatin inhibits SH-SY5Y neuroblastoma cell invasion and metastasis through PTEN signaling.
TL;DR: The results support the potential anti-metastatic effects of isatin on NB cells, which have been investigated as a potential anticancer agent.
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