Ning Ding
Indiana University
8 Papers
20 Citations
Ning Ding is an academic researcher from Indiana University. The author has contributed to research in topics: DNA methylation & DNA repair. The author has an hindex of 8, co-authored 8 publications.
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Papers
Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage
Ning Ding,Emily M. Bonham,Brooke E. Hannon,Thomas R. Amick,Stephen B. Baylin,Heather M. O'Hagan +5 more
TL;DR: In this paper, the mismatch repair protein heterodimer MSH2-MSH6 participates in the oxidative damage-induced recruitment of DNA methyltransferase 1 (DNMT1) to chromatin.
Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and Invasion.
Jessica Tang,Nicholas Pulliam,Ali R. Özeş,Aaron Buechlein,Ning Ding,Harold N. Keer,Doug Rusch,Heather M. O'Hagan,M. Sharon Stack,Kenneth P. Nephew +9 more
TL;DR: The effect of DNMT inhibitor on fully differentiated adipocytes suggests that hypomethylating agents may affect the tumor microenvironment to decrease cancer cell metastasis.
JAK2 regulates mismatch repair protein-mediated epigenetic alterations in response to oxidative damage.
TL;DR: It is demonstrated that in response to hydrogen peroxide (H2O2), JAK2 localizes to the nucleus and interacts with MSH2 and MSH6, which provides novel insight into the connection between kinase activation and epigenetic alterations during oxidative damage and inflammation.
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The Emerging Role of Epigenetic Modifiers in Repair of DNA Damage Associated with Chronic Inflammatory Diseases
Ning Ding,Ashley R. Maiuri,Heather M. O'Hagan +2 more
- 01 Jan 2017
TL;DR: In this article, the authors focus on the types of DNA damage and epigenetic alterations associated with chronic inflammatory diseases and how these modifications may result in epigenetic alteration. But, it is not clear how altered epigenetic gene silencing is initiated during chronic inflammation.
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Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and Invasion
Jessica Tang,Nicholas Pulliam,Ali R. Özeş,Aaron Buechlein,Ning Ding,Harold N. Keer,Doug Rusch,Heather M. O'Hagan,M. Sharon Stack,Kenneth P. Nephew +9 more
- 01 Aug 2018
TL;DR: In this article, the authors examined the effect of adipocytes on ovarian cancer cell behavior in culture and the impact of targeting DNA methylation in adipocyte on ovarian tumor metastasis.
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