5 Papers
Ning Bai is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: NMDA receptor & Excitotoxicity. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of Ning Bai include China Medical University (PRC).
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Papers
Astroglial glutamate transporter deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice.
Tomomi Aida,Junichi Yoshida,Masatoshi Nomura,Asami Tanimura,Yusuke Iino,Miho Soma,Ning Bai,Yukiko Ito,Wanpeng Cui,Hidenori Aizawa,Michiko Yanagisawa,Terumi Nagai,Norio Takata,Kenji F. Tanaka,Ryoichi Takayanagi,Masanobu Kano,Magdalena Götz,Hajime Hirase,Kohichi Tanaka +18 more
TL;DR: It is suggested that astroglial GLT1 has a critical role in controlling the synaptic efficacy at corticostriatal synapses and its dysfunction causes pathological repetitive behaviors in iKO mice.
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Effects of Different Doses of BDNF on Postoperative Cognitive Function in Aged Rats Undergoing Abdominal Surgery
TL;DR: Compared with 0.1 g/ L of BDNF, 0.2 g/L ofBDNF can improve the postoperative cognitive function of aged rats undergoing abdominal surgery.
Delta-like 1 regulates Bergmann glial monolayer formation during cerebellar development
TL;DR: The results suggest that Dll1 is required for the formation of the BG layer and its morphological maturation, apparently through a Notch1/2-RBPj dependent signaling pathway.
Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity
Ning Bai,Hideki Hayashi,Tomomi Aida,Kazuhiko Namekata,Takayuki Harada,Masayoshi Mishina,Kohichi Tanaka +6 more
TL;DR: It is demonstrated that NR2D deficiency attenuates RGC loss in GLAST-deficient mice, and Dock3, a guanine nucleotide exchange factor, binds to theNR2D C-terminal domain and reduces the surface expression of NR2 D, thereby protecting RGCs from excitotoxicity, suggesting that NR1- and NR2A- and/or NR2B-containing receptors may have a neuroprotective effect.
NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina
Ning Bai,Ning Bai,Tomomi Aida,Michiko Yanagisawa,Sayaka Katou,Kenji Sakimura,Masayoshi Mishina,Kohichi Tanaka +7 more
TL;DR: The data suggest that GluN2B- and GLUN2D-containing NMDARs play a critical role in NMDA-induced excitotoxic retinal cell death and RGC degeneration in glutamate aspartate transporter deficient mice.