Ninette Cohen
Sheba Medical Center
16 Papers
189 Citations
Ninette Cohen is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: Karyotype & Fluorescence in situ hybridization. The author has an hindex of 10, co-authored 16 publications.
Chat about Author
Papers
Subgroup of patients with Philadelphia-positive chronic myelogenous leukemia characterized by a deletion of 9q proximal to ABL gene: expression profiling, resistance to interferon therapy, and poor prognosis
Ninette Cohen,Galit Rozenfeld-Granot,Izhar Hardan,Frida Brok-Simoni,Ninette Amariglio,Gideon Rechavi,Luba Trakhtenbrot +6 more
TL;DR: In this article, a major deletion of the region proximal to the rearranged ABL gene on 9q was found in 14/94 (15%) of chronic myelogenous leukemia Philadelphia-positive patients by interphase fluorescent in situ hybridization with the BCR/ABL extra signal dual-color probe.
117
Immature leukemic CD34+CXCR4+ cells from CML patients have lower integrin-dependent migration and adhesion in response to the chemokine SDF-1.
Amnon Peled,Izhar Hardan,Luba Trakhtenbrot,Eyal Gur,Michal Magid,Merav Darash-Yahana,Ninette Cohen,Valentin Grabovsky,Suzana Franitza,Orit Kollet,Ofer Lider,Ronen Alon,Gideon Rechavi,Tsvee Lapidot +13 more
TL;DR: Findings suggest a major role for SDF‐1‐mediated, integrin‐dependent BM retention of Ph+CD34+ cells from newly diagnosed CML patients that express the chemokine receptor CXCR4.
87
Standardization criteria for the detection of BCR/ABL fusion in interphase nuclei of chronic myelogenous leukemia patients by fluorescence in situ hybridization.
Ninette Cohen,Ilya Novikov,Izhar Hardan,Arif Esa,Frida Brok-Simoni,Ninette Amariglio,Gideon Rechavi,Isaac Ben-Bassat,Luba Trakhtenbrot +8 more
TL;DR: This work presents their standardization criteria for clinical practice, which include not only the methods for cell fixation, specimen preparation, and hybridization conditions, but mainly the definition of false-positive range and the scoring criteria of microscopic analysis.
46
Karyotypic evolution pathways in medulloblastoma/primitive neuroectodermal tumor determined with a combination of spectral karyotyping, G-banding, and fluorescence in situ hybridization
Ninette Cohen,David R. Betts,Uri Tavori,Amos Toren,Tzvi Ram,Shlomi Constantini,Michael A. Grotzer,Ninette Amariglio,Gideon Rechavi,Luba Trakhtenbrot +9 more
TL;DR: The results showed that the karyotypic evolution process in these tumors is typically divergent and complex, followed by acquisition of additional numerical or structural aberrations (or both).
25
Detection of unidentified chromosome abnormalities in human neuroblastoma by spectral karyotyping (SKY).
Ninette Cohen,David R. Betts,Luba Trakhtenbrot,Felix Niggli,Ninette Amariglio,Frida Brok-Simoni,Gideon Rechavi,Dafna Meitar +7 more
TL;DR: Spectral karyotyping is a novel technique based on the simultaneous hybridization of 24 fluorescently labeled chromosome painting probes that allows identification not only of material gained and lost, but also of breakpoints and chromosomal associations.
22