Nimee K. Bhat
University of Missouri–Kansas City
11 Papers
62 Citations
Nimee K. Bhat is an academic researcher from University of Missouri–Kansas City. The author has contributed to research in topics: Oxidative stress & Resveratrol. The author has an hindex of 10, co-authored 11 publications.
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Papers
MicroRNA-93 regulates NRF2 expression and is associated with breast carcinogenesis
TL;DR: The role of vit C in the regulation of microRNA-93 and its target gene(s) in a rat model of mammary carcinogenesis is investigated and an oncogenic potential of miR-93 is suggested during E2-induced breast carcinogenesis.
Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways
Bhupendra Singh,Rivka L. Shoulson,Anwesha Chatterjee,Amruta Ronghe,Nimee K. Bhat,Daniel C. Dim,Hari K. Bhat +6 more
TL;DR: It is suggested that Res inhibits E2-induced breast carcinogenesis via induction of NRF2-mediated protective pathways.
Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer
TL;DR: The studies suggest that antioxidants Vit C and BHA provide protection against oxidative DNA damage and E2-induced mammary carcinogenesis, at least in part, through NRF2-mediated induction of OGG1.
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Dietary Quercetin Exacerbates the Development of Estrogen-Induced Breast Tumors in Female ACI Rats
Bhupendra Singh,Sarah M. Mense,Nimee K. Bhat,Sandeep Putty,William A. Guthiel,Fabrizio Remotti,Hari K. Bhat +6 more
TL;DR: Results indicate that quercetin (2.5 g/kg food) does not confer protection against breast cancer, does not inhibit E(2)-induced oxidant stress and may exacerbate breast carcinogenesis in E( 2)-treated ACI rats.
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Induction of NAD(P)H-quinone oxidoreductase 1 by antioxidants in female ACI rats is associated with decrease in oxidative DNA damage and inhibition of estrogen-induced breast cancer
TL;DR: The objective of the current study was to identify the mechanism of antioxidant-mediated protection against E2-induced DNA damage and mammary tumorigenesis and demonstrate that NQO1 upregulation by antioxidants is mediated through NRF2.
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