Nil Guzel
Kocaeli University
9 Papers
38 Citations
Nil Guzel is an academic researcher from Kocaeli University. The author has contributed to research in topics: Proteome & Mutant. The author has an hindex of 4, co-authored 9 publications.
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Papers
The prominent proteins expressed in healthy gingiva: a pilot exploratory tissue proteomics study
Emre Yaprak,Murat Kasap,Gurler Akpinar,Sibel Kayaalti-Yuksek,Alper Sinanoglu,Nil Guzel,Husniye Demirturk Kocasarac +6 more
TL;DR: An initial proteome map of the gingival tissue from healthy individuals was established and 2DE was an effective approach in studying the common protein expression profile of theGingiva.
20
Linking a compound-heterozygous Parkin mutant (Q311R and A371T) to Parkinson's disease by using proteomic and molecular approaches.
Sinem Ozgul,Murat Kasap,Gurler Akpinar,Aylin Kanli,Nil Guzel,Kubra Karaosmanoglu,Ahmet Tarik Baykal,Pervin Iseri +7 more
TL;DR: Overall, this study was able to create a possible link between a pair of Parkin mutations to its pertinent disease by using 2D-DIGE in combination with biochemical and molecular approaches.
16
Comparative proteome analysis of the tear samples in patients with low-grade keratoconus
TL;DR: The involvement of NADHX repair pathway in KC should be investigated, since preliminary clues obtained in this study point to that direction, and showing the presence of ATP-dependent NAD(P)H-hydrate dehydratase that eliminates NADHx would strengthen the findings and would be a major step toward understanding KC.
14
Proteomic analysis in endometrial cancer and endometrial hyperplasia tissues by 2D-DIGE technique.
Yasin Ceylan,Gurler Akpinar,Emek Doğer,Murat Kasap,Nil Guzel,Kubra Karaosmanoglu,Sule Yildirim Kopuk,İzzet Yücesoy +7 more
TL;DR: It was determined that the CAH1 and PPIB levels increased in more advanced stages of endometrial cancer, and the induction of CALR activity may be a factor that progresses apoptosis, thus, May be a hope for postoperative new chemotherapy treatment methods.
12
Exogenous Expressions of FTO Wild-Type and R316Q Mutant Proteins Caused an Increase in HNRPK Levels in 3T3-L1 Cells as Demonstrated by DIGE Analysis
TL;DR: This is the first study revealing the presence of a parallel increase in expressions of FTO and HNR NPK proteins, which may codictate the metabolic changes occurring in the cell and may attribute a significance to HNRNPK in FTO-associated transformations.