Niels E. Skakkebæk
University of Copenhagen
612 Papers
7.5K Citations
Niels E. Skakkebæk is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 127, co-authored 596 publications. Previous affiliations of Niels E. Skakkebæk include Copenhagen University Hospital & Hvidovre Hospital.
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Papers
Continuation of growth hormone (GH) replacement in GH-deficient patients during transition from childhood to adulthood: a two-year placebo-controlled study.
Nina Vahl,Anders Juul,Jens Otto Lunde Jørgensen,Hans Ørskov,Niels E. Skakkebæk,Jens Sandahl Christiansen +5 more
TL;DR: It is recommended that continuation of GH therapy in GHD patients, during the transition from childhood to adulthood, induces significant and potentially unfavorable changes in IGF-I and body composition, both of which are reversed after resumption of GH treatment.
Spermaturia and serum hormone concentrations at the age of puberty in boys prenatally exposed to polychlorinated biphenyls.
Nanette M. Mol,Nicolina Sørensen,Pal Weihe,Anna-Maria Andersson,Niels Jørgensen,Niels E. Skakkebæk,Niels Keiding,Philippe Grandjean +7 more
TL;DR: The findings support the validity of spermaturia as a useful indicator of puberty, although a substantial rate of false negatives must be taken into account.
Caffeine Intake and Semen Quality in a Population of 2,554 Young Danish Men
TL;DR: The authors cannot exclude the possibility of a threshold above which cola, and possibly caffeine, negatively affects semen quality, and the less healthy lifestyle of these men may explain these findings.
The spermatocytic seminoma: views on pathogenesis.
TL;DR: It is suggested that the spermatocytic seminoma has a different cell of origin from that of other germ cell tumours of the testis.
Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors.
Christina E. Hoei-Hansen,John E. Nielsen,Kristian Almstrup,Si Brask Sonne,Niels Graem,Niels E. Skakkebæk,Henrik Leffers,Ewa Rajpert-De Meyts +7 more
TL;DR: Investigation of ontogeny of AP-2γ protein expression in fetal gonads revealed that it was confined to oogonia/gonocytes and was down-regulated with germ cell differentiation, and is developmentally regulated and associated with the undifferentiated phenotype in germ cells.