Nicole Teller
Karlsruhe Institute of Technology
4 Papers
199 Citations
Nicole Teller is an academic researcher from Karlsruhe Institute of Technology. The author has contributed to research in topics: Receptor tyrosine kinase & Delphinidin. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of Nicole Teller include University of Vienna.
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Papers
Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs?
Sarah C. Thomasset,Nicole Teller,Hong Cai,Doris Marko,David P. Berry,William P. Steward,Andreas J. Gescher +6 more
TL;DR: In the light of their robust cancer chemopreventive efficacy in experimental models and their superior stability as compared to that of the aglycons, the Anthocyanins seem much more suitable for further drug development than their anthocyanidin counterparts.
Effect of coffee combining green coffee bean constituents with typical roasting products on the Nrf2/ARE pathway in vitro and in vivo.
Nadine Volz,Ute Boettler,Swantje Winkler,Nicole Teller,Christoph Schwarz,Tamara Bakuradze,Gerhard Eisenbrand,Larisa M. Haupt,Lyn R. Griffiths,Herbert Stiebitz,Gerhard Bytof,Ingo Lantz,Roman Lang,Thomas Hofmann,Veronika Somoza,Doris Marko +15 more
TL;DR: In this article, the authors investigated Nrf2-activating properties of a coffee blend combining raw coffee bean constituents with 5-O-caffeoylquinic acid (CGA) as a lead component with typical roasting products such as N-methylpyridinium (NMP).
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Suppression of the kinase activity of receptor tyrosine kinases by anthocyanin-rich mixtures extracted from bilberries and grapes.
Nicole Teller,Wilko Thiele,Timothy H. Marczylo,Andreas J. Gescher,Ute Boettler,Jonathan P. Sleeman,Doris Marko +6 more
TL;DR: Considering the important role of RTKs in carcinogenesis, their inhibition by anthocyanin-rich mixtures suggests that they may serve as biomarkers of the pharmacological efficacy of Anthocyanins in future chemoprevention experiments and in clinical intervention studies.
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Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation.
TL;DR: Whereas quercetin was most effective against the EGFR, delphinidin exhibited some preference towards the ErbB2 receptor, indicating a broader spectrum of activity against receptor tyrosine kinases.