Nicolas Picard
University of Zurich
7 Papers
77 Citations
Nicolas Picard is an academic researcher from University of Zurich. The author has contributed to research in topics: Cotransporter & Fibrosis. The author has an hindex of 7, co-authored 7 publications. Previous affiliations of Nicolas Picard include French Institute of Health and Medical Research & Centre national de la recherche scientifique.
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Papers
Tubular Overexpression of Transforming Growth Factor-β1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells
Robert Koesters,Brigitte Kaissling,Michel LeHir,Nicolas Picard,Franziska Theilig,Rolf Gebhardt,Adam B. Glick,Brunhilde Hähnel,Hiltraud Hosser,Hermann Josef Gröne,Wilhelm Kriz +10 more
TL;DR: In conclusion, overexpression of TGF-beta1 in renal tubules in vivo induces interstitial proliferation, tubular autophagy, and fibrosis, but not epithelial-to-mesenchymal transition.
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Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat
TL;DR: The fate of resident fibroblasts in the initial phase of renal fibrosis in the classical model of unilateral ureter obstruction in the rat showed progressive alterations, suggesting a transformation in myofibroblast, likely playing a central role in fibrosis.
Acute parathyroid hormone differentially regulates renal brush border membrane phosphate cotransporters
Nicolas Picard,Paola Capuano,Gerti Stange,Marija Mihailova,Brigitte Kaissling,Heini Murer,Jürg Biber,Carsten A. Wagner +7 more
TL;DR: In this paper, Parathyroid hormone (PTH) was shown to reduce NaPi-IIa staining in the brush border membrane (BBM) with increased intracellular and lysosomal appearance.
Protein Phosphatase 1 Inhibitor-1 Deficiency Reduces Phosphorylation of Renal NaCl Cotransporter and Causes Arterial Hypotension
Nicolas Picard,Nicolas Picard,Katja Trompf,Chao Ling Yang,R. Lance Miller,Monique Carrel,Dominique Loffing-Cueni,Robert A. Fenton,David H. Ellison,Johannes Loffing +9 more
TL;DR: I-1 is a DCT-enriched gene product that controls arterial BP, possibly through regulation of NCC activity.
Immunolocalization of phospho-S6 kinases: a new way to detect mitosis in tissue sections and in cell culture.
Thomas Schmidt,Patricia R. Wahl,Rudolf P. Wüthrich,Alexander Vogetseder,Nicolas Picard,Brigitte Kaissling,Michel Le Hir +6 more
TL;DR: In cryostat sections of perfusion-fixed tissue mitotic cells appeared as bright spots in immunofluorescence using an antibody specific for the phosphorylation site Thr421/Ser424, and immunohistochemistry with anti-phospho-S6 kinase appears to provide a convenient way to detectMitotic cells at low magnification.