Nicholas M Eckersley
St George's, University of London
8 Papers
6 Citations
Nicholas M Eckersley is an academic researcher from St George's, University of London. The author has contributed to research in topics: Medicine & Antibody. The author has an hindex of 3, co-authored 6 publications.
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Papers
Dynamics of IgG seroconversion and pathophysiology of COVID-19 infections
Henry M. Staines,Daniela E. Kirwan,David J Clark,Emily R. Adams,Yolanda Augustin,Rachel L Byrne,Michael Cocozza,Ana I Cubas-Atienza,Luis E. Cuevas,Martina Cusinato,Benedict M O Davies,Mark M. Davis,Paul A. Davis,Annelyse Duvoix,Nicholas M Eckersley,Daniel M. Forton,Alice J. Fraser,Gala Garrod,Linda Hadcocks,Qinxue Hu,Michael H. Johnson,Grant A Kay,Kesja Klekotko,Zawditu Lewis,Josephine Mensah-Kane,Stefanie Menzies,Irene M. Monahan,Catherine M. Moore,Gerhard Nebe-von-Caron,Sophie I Owen,Chris Sainter,Amadou A. Sall,James Schouten,Christopher T Williams,John T. Wilkins,Kevin Woolston,Joseph R Fitchett,Sanjeev Krishna,Tim Planche +38 more
TL;DR: Dynamics of seroconversion to SARS-CoV-2 infections detected by IgG ELISA in 177 individuals diagnosed by RT-PCR are reported and higher antibody responses are associated with symptomatic disease, older age, ethnicity, increased co-morbidity and higher inflammatory markers such as C Reactive Protein.
Rapid development of COVID-19 rapid diagnostics for low resource settings: accelerating delivery through transparency, responsiveness, and open collaboration
Emily R. Adams,Yolanda Augustin,Rachel L Byrne,David J Clark,Michael Cocozza,Ana I Cubas-Atienzar,Luis E. Cuevas,Martina Cusinato,Benedict M O Davies,Mark S. Davies,Paul Davies,Annelyse Duvoix,Nicholas M Eckersley,Thomas Edwards,Tom Fletcher,Alice J. Fraser,Gala Garrod,Linda Hadcocks,Qinxue Hu,Michael H. Johnson,Grant A Kay,Katherin Keymer,Daniela E. Kirwan,Kesja Klekotko,Zawditu Lewis,Jenifer C. Mason,Josie Mensah-Kane,Stefanie Menzies,Irene M. Monahan,Catherine M. Moore,Gerhard Nebe-von-Caron,Sophie I Owen,Tim Planche,Chris Sainter,James Schouten,Henry M. Staines,Lance Turtle,Lance Turtle,Christopher T Williams,John T. Wilkins,Kevin Woolston,Amadou A. Sall,Joseph R Fitchett,Sanjeev Krishna +43 more
TL;DR: This is the first in a series of Mologic products for CO VID-19, which will be deployed for COVID-19 diagnosis, contact tracing and sero-epidemiological studies to estimate disease burden and transmission with a focus on ensuring access, affordability, and availability to lowest resource settings.
Production and use of encapsidated RNA mimics as positive control reagents for SARS-CoV-2 RT-qPCR diagnostics.
Hadrien Peyret,Elisabetta Groppelli,David J Clark,Nicholas M Eckersley,Tim Planche,Julian Ma,George P. Lomonossoff +6 more
TL;DR: In this article, the authors describe a custom RNA packaging system from the plant virus cowpea mosaic virus to produce virus-like particles that encapsidate specifically designed portions of the genome of SARS-CoV-2, the causative agent of COVID-19.
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SARS-CoV-2 Vaccine Immunogenicity in Patients with Gastrointestinal Cancer Receiving Systemic Anti-Cancer Therapy
David K. Lau,Maria Aresu,Tim Planche,Amina Tran,Retchel Lazaro-Alcausi,J Duncan,Shannon Kidd,Susan Cromarty,Ruwaida Begum,Isma Rana,Su Li,Ali Abdulnabi Mohamed,Irene M. Monahan,David M. Clark,Nicholas M Eckersley,Henry M. Staines,Elisabetta Groppelli,Sanjeev Krishna,Martin Mayora-Neto,Nigel J. Temperton,Charlotte Fribbens,David Watkins,Naureen Starling,Ian Chau,David Cunningham,Sheela Rao +25 more
TL;DR: In this paper , the authors conducted a prospective study to evaluate the prevalence of neutralizing antibodies in a cohort of GI cancer patients receiving chemotherapy following SARS-CoV-2 vaccination.
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The QuantuMDx Q-POC SARS-CoV-2 RT-PCR assay for rapid detection of COVID-19 at point-of-care: preliminary evaluation of a novel technology
Jessica Caffry,Matthew Selby,Katie Barr,George Morgan,David McGurk,Philip Scully,Catherine Park,Anna-Maria Caridis,Emily Southworth,Jack Morrison,David J Clark,Nicholas M Eckersley,Elisabetta Groppelli,Daniela E. Kirwan,Irene M. Monahan,Yolanda Augustin,Colin Toombs,Tim Planche,Tim Planche,Henry M. Staines,Sanjeev Krishna +20 more
TL;DR: In this paper, a preliminary prospective performance evaluation of the QuantuMDx Q-POC™ SARS CoV-2 RT-PCR assay is presented, where the authors compare the sensitivity and specificity of the Q-pOC™ test against a reference laboratory-based RTPCR.