Nicholas H. Hunt
Australian National University
28 Papers
422 Citations
Nicholas H. Hunt is an academic researcher from Australian National University. The author has contributed to research in topics: Plasmodium vinckei & Adenylate kinase. The author has an hindex of 17, co-authored 28 publications. Previous affiliations of Nicholas H. Hunt include University of New South Wales.
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Papers
Free radical-induced pathology
Abstract: 53 (1983).
149
Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate acetate and ionomycin
TL;DR: The results suggest that free radicals are involved in specific early events in T-cell activation, which is quite distinct from the inhibition of proliferation caused by HU.
103
Changes in hormone responsiveness and cyclic AMP metabolism in rat hepatocytes during primary culture and effects of supplementing the medium with insulin and dexamethasone
Thoralf Christoffersen,Magne Refsnes,Gunnar O. Brønstad,Eva Østby,Jörgen Huse,Frode Haffner,Tor-Erik Sand,Nicholas H. Hunt,Ole Sonne +8 more
TL;DR: The results suggest that insulin and glucocorticoids modulate the effects of glucagon and epinephrine on hepatocytes by exerting long-term influences on the cyclic AMP system.
97
Activity of divicine in Plasmodium vinckei‐infected mice has implications for treatment of favism and epidemiology of G‐6‐PD deficiency
TL;DR: These observations support the hypothesis advanced by Huheey & Martin to explain the patchy geographical distribution of glucose‐6‐phosphate dehydrogenase deficiency in historic malarial areas and suggest that desferrioxamine, a drug already in clinical use, is a potential treatment for favism and other examples of oxidative haemolysis.
50
Detection of short-chain carbonyl products of lipid peroxidation from malaria-parasite (Plasmodium vinckei)-infected red blood cells exposed to oxidative stress.
TL;DR: It is demonstrated that products of lipid peroxidation other than malonaldehyde are formed during the exposure of malaria-infected RBCs in vitro to drugs that generate reactive oxygen species and have anti-parasitic activity.