Ni Ji
Harvard University
16 Papers
48 Citations
Ni Ji is an academic researcher from Harvard University. The author has contributed to research in topics: Wnt signaling pathway & Neuroblast. The author has an hindex of 7, co-authored 16 publications. Previous affiliations of Ni Ji include Massachusetts Institute of Technology & Picower Institute for Learning and Memory.
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Papers
Pan-neuronal imaging in roaming Caenorhabditis elegans
Vivek Venkatachalam,Ni Ji,Xian-Ling Wang,Christopher Luce Clark,James K. Mitchell,Mason Klein,Christopher J. Tabone,Jeremy Florman,Hongfei Ji,Joel Greenwood,Andrew D. Chisholm,Jagan Srinivasan,Mark J. Alkema,Mei Zhen,Mei Zhen,Aravinthan D. T. Samuel +15 more
TL;DR: It is shown that it is possible to uncover representations of sensory input and motor output in individual neurons of behaving animals from brainwide dynamics and an imaging setup and analysis pipeline should facilitate mapping circuits for sensory to motor transformation in transparent behaving animals such as C. elegans and Drosophila larva.
The thrombospondin repeat containing protein MIG-21 controls a left-right asymmetric Wnt signaling response in migrating C. elegans neuroblasts.
Teije C. Middelkoop,Lisa Williams,Pei-Tzu Yang,Jeroen Luchtenberg,Marco C. Betist,Ni Ji,Alexander van Oudenaarden,Cynthia Kenyon,Hendrik C. Korswagen +8 more
TL;DR: The stereotypic migration of the C. elegans Q neuroblasts is used as a model to study how two initially equivalent cells are instructed to activate either β-catenin dependent or independent Wnt signaling pathways to control the migration of their descendants along the anteroposterior axis.
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Corollary discharge promotes a sustained motor state in a neural circuit for navigation
Ni Ji,Vivek Venkatachalam,Hillary Denise Rodgers,Hillary Denise Rodgers,Wesley Hung,Wesley Hung,Taizo Kawano,Taizo Kawano,Christopher M. Clark,Maria Lim,Maria Lim,Mark J. Alkema,Mei Zhen,Mei Zhen,Aravinthan D. T. Samuel +14 more
TL;DR: In this article, the authors show that Caenorhabditis elegans uses feedback from the motor circuit to a sensory processing interneuron to sustain its motor state during thermotactic navigation.
Corollary Discharge Promotes a Sustained Motor State in a Neural Circuit for Navigation
Ni Ji,Vivek Venkatachalam,Hillary Denise Rodgers,Hillary Denise Rodgers,Wesley Hung,Taizo Kawano,Christopher M. Clark,Maria Lim,Mark J. Alkema,Mei Zhen,Aravinthan D. T. Samuel +10 more
TL;DR: It is proposed that feedback from the motor circuit to the sensory processing circuit underlies a positive feedback mechanism to generate persistent neural activity and sustained behavioral patterns in a sensorimotor transformation.
Hydra: Imaging Nerve Nets in Action
Ni Ji,Steven W. Flavell +1 more
TL;DR: New research has taken advantage of the unique biology of an ancient organism to bring us a step closer to mapping whole-brain activity during behavior.
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