Neta Nudel
Weizmann Institute of Science
2 Papers
Neta Nudel is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Golgi apparatus & Chemistry. The author has an hindex of 2, co-authored 2 publications.
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Papers
Golgi organization is regulated by proteasomal degradation.
Avital Eisenberg-Lerner,Ron Benyair,Noa Hizkiahou,Neta Nudel,Roey Maor,Matthias P. Kramer,Merav D. Shmueli,Inbal Zigdon,Marina Cherniavsky Lev,Adi Ulman,Jitka Yehudith Sagiv,Molly Dayan,Bareket Dassa,Mercedes Rosenwald,Idit Shachar,Jie Li,Yanzhuang Wang,Nili Dezorella,Suman Khan,Ziv Porat,Eyal Shimoni,Ori Avinoam,Yifat Merbl +22 more
TL;DR: Stress-induced degradation of GM130 by Golgi-localized 26S proteasomes, leading to Golgi dispersal is identified, providing a functional link between proteostasis control and Golgi architecture, which may be critical in various secretion-related pathologies.
Revealing the cellular degradome by mass spectrometry analysis of proteasome-cleaved peptides.
Hila Wolf-Levy,Aaron Javitt,Avital Eisenberg-Lerner,Assaf Kacen,Adi Ulman,Daoud Sheban,Bareket Dassa,Vered Fishbain-Yoskovitz,Carmelo Carmona-Rivera,Matthias P. Kramer,Neta Nudel,Ifat Regev,Liron Zahavi,Dalia Elinger,Mariana J. Kaplan,David Morgenstern,Yishai Levin,Yifat Merbl +17 more
TL;DR: Application of MAPP to cancer cell lines as well as primary immune cells revealed dynamic modulation of the cellular degradome in response to various stimuli, such as proinflammatory signals, suggesting a role of aberrant proteasomal degradation in the pathophysiology of SLE.
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