Neil M.H. Graham
Regeneron
239 Papers
2.4K Citations
Neil M.H. Graham is an academic researcher from Regeneron. The author has contributed to research in topics: Dupilumab & Medicine. The author has an hindex of 62, co-authored 237 publications. Previous affiliations of Neil M.H. Graham include Johns Hopkins University & CSL Limited.
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Papers
Association between serum vitamin A and E levels and HIV-1 disease progression.
TL;DR: It is suggested that high serum levels of vitamin E may be associated with slower HIV-1 disease progression, but no relationship was observed between retinol levels and disease progression in this vitamin A-replete population.
•Journal Article
Efficacy of Dupilumab in Different Racial Subgroups of Adults With Moderate-to-Severe Atopic Dermatitis in Three Randomized, Placebo-Controlled Phase 3 Trials
Andrew F Alexis,Marta I. Rendon,Jonathan I. Silverberg,David M. Pariser,Benjamin Lockshin,Christopher E.M. Griffiths,Jamie Weisman,Andreas Wollenberg,Zhen Chen,John D. Davis,Meng Li,Laurent Eckert,Abhijit Gadkari,Brad Shumel,Ana B. Rossi,Neil M.H. Graham,Marius Ardeleanu +16 more
TL;DR: Significant clinical improvement and a favorable benefit-risk profile can be achieved with dupilumab treatment in patients of White, Asian, and Black/African American racial subgroups with moderate-to-severe AD inadequately controlled with topical medications.
Dupilimab Efficacy in Patients with Uncontrolled, Moderate-to-Severe Asthma by Body Mass Index
Stephanie Korn,William W. Busse,Jose Echave-Sustaeta,Anne E. Dixon,Janos Mucsi,Megan S. Rice,Yamo Deniz,Paul Rowe,Heribert Staudinger,Nikhil Amin,Marcella Ruddy,Neil M.H. Graham,Ariel Teper +12 more
TL;DR: In the phase 3 QUEST trial (NCT02414854), add-on DPL 200/300 mg every 2 wks (q2w) vs placebo (PBO) as discussed by the authors reduced severe exacerbations and improved pre-bronchodilator (BD) FEV1 in patients with uncontrolled, moderate-to-severe asthma.
Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma
Ashish Bansal,Eric L. Simpson,Amy S. Paller,Elaine C. Siegfried,Elaine C. Siegfried,Andrew Blauvelt,Marjolein S. de Bruin-Weller,Jonathan Corren,Lawrence Sher,Emma Guttman-Yassky,Emma Guttman-Yassky,Zhen Chen,Nadia Daizadeh,Mohamed A. Kamal,Brad Shumel,Paola Mina-Osorio,Leda Mannent,Naimish Patel,Neil M.H. Graham,Faisal A. Khokhar,Marius Ardeleanu +20 more
TL;DR: In this paper, the authors evaluated the incidence and severity of conjunctivitis in dupilumab clinical trials in adolescents with moderate-to-severe atopic dermatitis or uncontrolled asthma.
The effects on survival of early treatment of human immunodeficiency virus infection.
Neil M.H. Graham,Scott L. Zeger,Lawrence P. Park,Sten H. Vermund,Roger Detels,Charles R. Rinaldo,John P. Phair +6 more
TL;DR: The hypothesis that in HIV-1 infection, early treatment with zidovudine and PCP prophylaxis improves survival in addition to slowing the progression to AIDS is supported.