Neal L. Benowitz
University of California, San Francisco
826 Papers
9K Citations
Neal L. Benowitz is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Nicotine & Cotinine. The author has an hindex of 126, co-authored 792 publications. Previous affiliations of Neal L. Benowitz include Shaare Zedek Medical Center & University College London.
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Papers
Emerging Nicotine Delivery Products. Implications for Public Health
TL;DR: E-cigarettes or other clean nicotine delivery devices could play an important role as an adjunct to a U.S. Food and Drug Administration regulatory intervention to make cigarettes less addictive and in this context could contribute to the end of cigarette smoking and smoking-induced disease.
Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine.
Gary E. Swan,Christina N. Lessov-Schlaggar,Andrew W. Bergen,Yungang He,Rachel F. Tyndale,Neal L. Benowitz +5 more
TL;DR: A combined genetic epidemiologic and pharmacogenetic investigation of the 3HC/COT ratio in plasma and urine concluded that additive genetic factors are prominent in determining variation in plasma 3HC /COT but less so in deciding variation in urine 3HC./COT.
Transferability of Ancestry-Specific and Cross-Ancestry CYP2A6 Activity Genetic Risk Scores in African and European Populations
Ahmed El-Boraie,Ahmed El-Boraie,Meghan J. Chenoweth,Meghan J. Chenoweth,Jennie G. Pouget,Jennie G. Pouget,Neal L. Benowitz,Koya Fukunaga,Taisei Mushiroda,Michiaki Kubo,Nicole L. Nollen,Lisa Sanderson Cox,Caryn Lerman,Jo Knight,Rachel F. Tyndale,Rachel F. Tyndale +15 more
TL;DR: The findings establish the clinical benefit of applying ancestry-specific wGRSs, demonstrating superiority of the AFR wG RS in AFRs, and demonstrate model robustness against known environmental sources of NMR variation.
The Role of Nicotine in Smoking-Related Cardiovascular Disease☆☆☆
TL;DR: Clinical studies of pipe smokers and people using transdermal nicotine support the idea that toxins other than nicotine are the most important causes of acute cardiovascular events, and the dose response for cardiovascular events of nicotine appears to be flat, suggesting that if nicotine is involved, adverse effects might be seen with relatively low-level cigarette exposures.
Smokeless tobacco as a nicotine delivery device: harm or harm reduction?
TL;DR: Controversy pertaining to ST and health, the pros and cons of ST in harm reduction, and progress in treatment for those who would like to quit ST use are discussed.